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Fetal and neonatal lung development : clinical correlates and technologies for the future / edited by Alan H. Jobe, Jeffrey A. Whitsett, Steven H. Abman.

Contributor(s): Material type: TextTextPublisher: New York : Cambridge University Press, 2016Description: 1 online resource (ix, 324 pages) : digital, PDF file(s)Content type:
  • text
Media type:
  • computer
Carrier type:
  • online resource
ISBN:
  • 9781139680349 (ebook)
Other title:
  • Fetal & Neonatal Lung Development
Subject(s): Additional physical formats: Print version: : No titleDDC classification:
  • 618.922/4 23
LOC classification:
  • RJ312 .F48 2016
Online resources:
Contents:
The genetic programs regulating embryonic lung development and induced pluripotent stem cell differentiation / Finn Hawkins, Scott A Rankin, Darrell N. Kotton, and Aaron M. Zorn -- Early development of the mammalian lung-branching morphogenesis / Kathleen M. Stewart and Edward E. Morrisey -- Pulmonary vascular development / Timothy D. Le Cras and Marlene Rabinovitch -- Transcriptional mechanisms regulating pulmonary epithelial maturation : a systems biology approach / Jeffrey A. Whitsett and Yan Xu -- Environmental effects on lung morphogenesis and function : tobacco products, combustion products and other sources of pollution / Cindy T. McEvoy & Eliot R. Spindel -- Congenital malformations of the lung / Susan E. Wert and Kathryn A. Wikenheiser-Brokamp -- Lung structure at preterm and term birth / Jason C. Woods and Johannes C. Schittny -- Surfactant during lung development / Timothy E. Weaver, Lawrence M. Nogee, and Alan H. Jobe -- Initiation of breathing at birth / Arjan te Pas and Stuart Hooper -- Perinatal modifiers of lung structure and function / Suhas G. Kallapur and Sailesh Kotecha -- Chronic neonatal lung injury and care strategies to decrease injury / Robert P. Jankov and A. Keith Tanswel -- Apnea and control of breathing / Christopher C. Stryker, Andrew Dylag, and Richard J. Martin -- Alveolarization into adulthood / Manjith Narayanan -- Physiologic assessment of lung growth and development throughout infancy and childhood / Anne-Marie Gibson, Sarath Ranganathan, and Lex W Doyle -- Perinatal disruptions of lung development : mechanisms and implications for chronic lung diseases / Michael A. O'Reilly -- Lung growth through the "life course" and predictors and determinants of chronic respiratory disorders / Fernando D. Martinez -- The lung structure maintenance program : sustaining lung structure during adulthood and implications for COPD risk / Norbert F. Voelkel and Masahiro Sakagami.
Summary: Lung disease affects more than 600 million people worldwide. While some of these lung diseases have an obvious developmental component, there is growing appreciation that processes and pathways critical for normal lung development are also important for postnatal tissue homeostasis and are dysregulated in lung disease. This book provides an authoritative review of fetal and neonatal lung development designed to provide a diverse group of scientists, spanning the basic to clinical research spectrum, with the latest developments on the cellular and molecular mechanisms of normal lung development and injury-repair processes, and how they are dysregulated in disease. The book includes genetics, omics, and systems biology as well as new imaging techniques that are transforming studies of lung development. The reader will learn where the field of lung development has been, where it is presently, and where it is going to improve outcomes for patients with common and rare lung diseases.
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The genetic programs regulating embryonic lung development and induced pluripotent stem cell differentiation / Finn Hawkins, Scott A Rankin, Darrell N. Kotton, and Aaron M. Zorn -- Early development of the mammalian lung-branching morphogenesis / Kathleen M. Stewart and Edward E. Morrisey -- Pulmonary vascular development / Timothy D. Le Cras and Marlene Rabinovitch -- Transcriptional mechanisms regulating pulmonary epithelial maturation : a systems biology approach / Jeffrey A. Whitsett and Yan Xu -- Environmental effects on lung morphogenesis and function : tobacco products, combustion products and other sources of pollution / Cindy T. McEvoy & Eliot R. Spindel -- Congenital malformations of the lung / Susan E. Wert and Kathryn A. Wikenheiser-Brokamp -- Lung structure at preterm and term birth / Jason C. Woods and Johannes C. Schittny -- Surfactant during lung development / Timothy E. Weaver, Lawrence M. Nogee, and Alan H. Jobe -- Initiation of breathing at birth / Arjan te Pas and Stuart Hooper -- Perinatal modifiers of lung structure and function / Suhas G. Kallapur and Sailesh Kotecha -- Chronic neonatal lung injury and care strategies to decrease injury / Robert P. Jankov and A. Keith Tanswel -- Apnea and control of breathing / Christopher C. Stryker, Andrew Dylag, and Richard J. Martin -- Alveolarization into adulthood / Manjith Narayanan -- Physiologic assessment of lung growth and development throughout infancy and childhood / Anne-Marie Gibson, Sarath Ranganathan, and Lex W Doyle -- Perinatal disruptions of lung development : mechanisms and implications for chronic lung diseases / Michael A. O'Reilly -- Lung growth through the "life course" and predictors and determinants of chronic respiratory disorders / Fernando D. Martinez -- The lung structure maintenance program : sustaining lung structure during adulthood and implications for COPD risk / Norbert F. Voelkel and Masahiro Sakagami.

Lung disease affects more than 600 million people worldwide. While some of these lung diseases have an obvious developmental component, there is growing appreciation that processes and pathways critical for normal lung development are also important for postnatal tissue homeostasis and are dysregulated in lung disease. This book provides an authoritative review of fetal and neonatal lung development designed to provide a diverse group of scientists, spanning the basic to clinical research spectrum, with the latest developments on the cellular and molecular mechanisms of normal lung development and injury-repair processes, and how they are dysregulated in disease. The book includes genetics, omics, and systems biology as well as new imaging techniques that are transforming studies of lung development. The reader will learn where the field of lung development has been, where it is presently, and where it is going to improve outcomes for patients with common and rare lung diseases.

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