Reconceiving the gene [electronic resource] : Seymour Benzer's adventures in phage genetics / Frederic Lawrence Holmes ; edited by William C. Summers.
By: Holmes, Frederic Lawrence
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Contributor(s): Summers, William C.
Material type: 
TextPublisher: New Haven : Yale University Press, c2006Description: 1 online resource (ix, 334 p.) : ill.ISBN: 9780300129700 (electronic bk.); 030012970X (electronic bk.); 1281730475; 9781281730473.Subject(s): Benzer, Seymour | Benzer, Seymour | Geneticists -- United States -- Biography | Bacteriophages -- Genetics | Viral genetics -- History | Bacteriophage T4 -- genetics | Genetics, Microbial -- Biography | Chromosome Mapping | Genome, Bacterial | SCIENCE -- Life Sciences -- Genetics & Genomics | BIOGRAPHY & AUTOBIOGRAPHY -- Science & Technology | Genetica | Microbiologie | Bacteriofagen | Geneticists -- United States | გენეტიკა-- ბაქტერიოფაგებიGenre/Form: Electronic books.Additional physical formats: Print version:: Reconceiving the gene.DDC classification: 576.5092 | B LOC classification: QH429.2.B46 | H65 2006ebOnline resources: EBSCOhost | Item type | Current location | Call number | Status | Date due | Barcode |
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ელ.რესურსი
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ეროვნული სამეცნიერო ბიბლიოთეკა 1 | 576 (Browse shelf) | Available |
Includes bibliographical references (p. [303]-329) and index.
Classical mendelian genetics -- Genetics and the phage biologists -- The physicist becomes a phage biologist -- To Paris and back -- Teaching and research at Purdue -- Entering the rII region -- Crossing into the fine structure -- Is gene a dirty word? -- The survival of the "gene."
A fascinating and detailed chronicle, "Reconceptualizing the Gene" relates how, between 1954 and 1961, the biologist Seymour Benzer mapped the fine structure of the rII region of the genome of the bacterial virus known as phage T4. Benzer's accomplishments and discoveries are widely recognized as a tipping point in mid-twentieth-century molecular biology when the nature of the gene was recast in molecular terms. More often than any other individual, he is considered to have led geneticists from the classical gene into the molecular age. Drawing on Benzer's remarkably complete record of his experiments, his correspondence, and published sources, Frederic Lawrence Holmes reconstructs how the former physicist initiated his work in phage biology, and how he accomplished his landmark investigation. The book follows Benzer's investigative pathway as his research unfolded and shifted, and as he adapted to opportunities or disappointments as they arose. The story of Benzer's creativity as a researcher is a fascinating story that also reveals intriguing aspects common to the scientific enterprise.
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