National Science Library of Georgia

Neurobiology of obesity /

Neurobiology of obesity / [edited by] Jenni Harvey, Dominic J. Withers. - Cambridge : Cambridge University Press, 2008. - 1 online resource (xii, 324 pages) : digital, PDF file(s).

Title from publisher's bibliographic system (viewed on 05 Oct 2015).

Introductory chapter / Benjamin C.T. Field, Caroline J. Small and Stephen R. Bloom -- Genetics of human and rodent body weight regulation / Karine Clément -- Hypothalamic control of energy homeostasis / Neel S. Singhal and Rexford S. Ahima -- Leptin and insulin as adiposity signals / Kevin D. Niswender -- Convergence of leptin and insulin signaling networks in obesity / Calum Sutherland and Mike Ashford -- Diet-induced obesity in animal models and what they tell us about human obesity / Barry E. Levin and Alison M. Strack -- Melanocortins and the control of body weight / Virginie Tolle and Malcolm J. Low -- Role of opiate peptides in regulating energy balance / Richard J. Bodnar and Allen S. Levine -- Ghrelin : an orexigenic signal from the stomach / Tamas Horvath -- Central nervous system controls of adipose tissue apoptosis / Mary Anne Della-Fera, Mark W. Hamrick and Clifton A. Baile -- Potential therapies to limit obesity / Jason C.G. Halford.

Obesity is one of the prime contributors to ill health in modern society, affecting around 20-25% of the population. It can cause or exacerbate a variety of health problems and is often associated with several other diseases including type II diabetes, coronary heart disease and certain types of cancer. Significant progress has been made in understanding the role of the nervous system and, in particular, the complex interplay between a range of orexigenic and anorectic agents within specific hypothalamic nuclei in the regulation of energy balance, appetite and adiposity. Several different neuronal pathways, neurotransmitters and hormones have been identified as major players in the regulation of feeding behavior and body weight and these are now being targeted as having therapeutic potential. Written for academic researchers and graduate students, Neurobiology of Obesity is a concise overview of recent developments in this field, written by leading international experts.

9780511541643 (ebook)


Obesity--Etiology.
Obesity--Pathophysiology.

RC628 / .N387 2008

616.398
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