Bioinformatics and computational biology in drug discovery and development / (Record no. 515910)
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| 000 -LEADER | |
|---|---|
| fixed length control field | 03220nam a22003378i 4500 |
| 001 - CONTROL NUMBER | |
| control field | CR9780511989421 |
| 003 - CONTROL NUMBER IDENTIFIER | |
| control field | UkCbUP |
| 005 - DATE AND TIME OF LATEST TRANSACTION | |
| control field | 20200124160212.0 |
| 006 - FIXED-LENGTH DATA ELEMENTS--ADDITIONAL MATERIAL CHARACTERISTICS--GENERAL INFORMATION | |
| fixed length control field | m|||||o||d|||||||| |
| 007 - PHYSICAL DESCRIPTION FIXED FIELD--GENERAL INFORMATION | |
| fixed length control field | cr|||||||||||| |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION | |
| fixed length control field | 101018s2016||||enk o ||1 0|eng|d |
| 020 ## - INTERNATIONAL STANDARD BOOK NUMBER | |
| International Standard Book Number | 9780511989421 (ebook) |
| 020 ## - INTERNATIONAL STANDARD BOOK NUMBER | |
| Cancelled/invalid ISBN | 9780521768009 (hardback) |
| 040 ## - CATALOGING SOURCE | |
| Original cataloging agency | UkCbUP |
| Language of cataloging | eng |
| Description conventions | rda |
| Transcribing agency | UkCbUP |
| 050 04 - LIBRARY OF CONGRESS CALL NUMBER | |
| Classification number | RM301.25 |
| Item number | .B56 2016 |
| 082 00 - DEWEY DECIMAL CLASSIFICATION NUMBER | |
| Classification number | 615.1/9 |
| Edition number | 23 |
| 245 00 - TITLE STATEMENT | |
| Title | Bioinformatics and computational biology in drug discovery and development / |
| Statement of responsibility, etc | edited by William T. Loging. |
| 246 3# - VARYING FORM OF TITLE | |
| Title proper/short title | Bioinformatics & Computational Biology in Drug Discovery & Development |
| 264 #1 - Production, Publication, Distribution, Manufacture, and Copyright Notice (R) | |
| Place of production, publication, distribution, manufacture (R) | Cambridge : |
| Name of producer, publisher, distributor, manufacturer (R) | Cambridge University Press, |
| Date of production, publication, distribution, manufacture, or copyright notice | 2016. |
| 300 ## - PHYSICAL DESCRIPTION | |
| Extent | 1 online resource (xi, 233 pages) : |
| Other physical details | digital, PDF file(s). |
| 336 ## - Content Type (R) | |
| Content type term (R) | text |
| Content type code (R) | txt |
| Source (NR) | rdacontent |
| 337 ## - Media Type (R) | |
| Media type term (R) | computer |
| Media type code (R) | c |
| Source (NR) | rdamedia |
| 338 ## - Carrier Type (R) | |
| Carrier type term (R) | online resource |
| Carrier type code (R) | cr |
| Source (NR) | rdacarrier |
| 500 ## - GENERAL NOTE | |
| General note | Title from publisher's bibliographic system (viewed on 05 Feb 2016). |
| 505 8# - FORMATTED CONTENTS NOTE | |
| Formatted contents note | Machine generated contents note: Foreword; Preface: the future of drug discovery and health care / Eric Schadt; 1. The art and science of the Drug Discovery Pipeline (DDP) / William T. Loging; 2. Computational approaches to drug target identification / Thomas B. Freeman and Pek Lum; 3. Understanding human disease knowledge through text mining / Raul Rodriguez-Esteban; 4. Integrating translational biomarkers into drug development / Jonathan Phillips; 5. Computational phenotypic assessment of small molecules in drug discovery / William T. Loging and Thomas B. Freeman; 6. Data visualization and the DDP process / Ke Xu; 7. Information visualization - important IT considerations / Telmo Silva; 8. The New Drug Application (NDA) and regulatory approval stages / William T. Loging, Marilyn Lewis, Bryn Williams-Jones and Roy Mansfield; 9. Clinical trial failures and drug repositioning / Mark Crawford and Jeff Handler; Appendix I. Additional knowledge-based analysis approaches / Raul Rodriguez-Esteban; Appendix II. Open source tools and public data sources / Yirong Wang and William T. Loging; Index. |
| 520 ## - SUMMARY, ETC. | |
| Summary, etc | Computational biology drives discovery through its use of high-throughput informatics approaches. This book provides a road map of the current drug development process and how computational biology approaches play a critical role across the entire drug discovery pipeline. Through the use of previously unpublished, real-life case studies the impact of a range of computational approaches are discussed at various phases of the pipeline. Additionally, a focus section provides innovative visualisation approaches, from both the drug discovery process as well as from other fields that utilise large datasets, recognising the increasing use of such technology. Serving the needs of early career and more experienced scientists, this up-to-date reference provides an essential introduction to the process and background of drug discovery, highlighting how computational researchers can contribute to that pipeline. |
| 650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name as entry element | Drug development. |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Loging, William T., |
| Relator term | editor. |
| 776 08 - ADDITIONAL PHYSICAL FORM ENTRY | |
| Display text | Print version: |
| International Standard Book Number | 9780521768009 |
| 856 40 - ELECTRONIC LOCATION AND ACCESS | |
| Uniform Resource Identifier | <a href="https://doi.org/10.1017/CBO9780511989421">https://doi.org/10.1017/CBO9780511989421</a> |
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