Recombinant antibodies for immunotherapy / (Record no. 521730)
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| 000 -LEADER | |
|---|---|
| fixed length control field | 04258nam a22003378i 4500 |
| 001 - CONTROL NUMBER | |
| control field | CR9780511596773 |
| 003 - CONTROL NUMBER IDENTIFIER | |
| control field | UkCbUP |
| 005 - DATE AND TIME OF LATEST TRANSACTION | |
| control field | 20200124160319.0 |
| 006 - FIXED-LENGTH DATA ELEMENTS--ADDITIONAL MATERIAL CHARACTERISTICS--GENERAL INFORMATION | |
| fixed length control field | m|||||o||d|||||||| |
| 007 - PHYSICAL DESCRIPTION FIXED FIELD--GENERAL INFORMATION | |
| fixed length control field | cr|||||||||||| |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION | |
| fixed length control field | 090716s2009||||enk o ||1 0|eng|d |
| 020 ## - INTERNATIONAL STANDARD BOOK NUMBER | |
| International Standard Book Number | 9780511596773 (ebook) |
| 020 ## - INTERNATIONAL STANDARD BOOK NUMBER | |
| Cancelled/invalid ISBN | 9780521887328 (hardback) |
| 040 ## - CATALOGING SOURCE | |
| Original cataloging agency | UkCbUP |
| Language of cataloging | eng |
| Description conventions | rda |
| Transcribing agency | UkCbUP |
| 050 00 - LIBRARY OF CONGRESS CALL NUMBER | |
| Classification number | RM282.M65 |
| Item number | R43 2009 |
| 082 00 - DEWEY DECIMAL CLASSIFICATION NUMBER | |
| Classification number | 615/.37 |
| Edition number | 22 |
| 245 00 - TITLE STATEMENT | |
| Title | Recombinant antibodies for immunotherapy / |
| Statement of responsibility, etc | edited by Melvyn Little. |
| 264 #1 - Production, Publication, Distribution, Manufacture, and Copyright Notice (R) | |
| Place of production, publication, distribution, manufacture (R) | Cambridge : |
| Name of producer, publisher, distributor, manufacturer (R) | Cambridge University Press, |
| Date of production, publication, distribution, manufacture, or copyright notice | 2009. |
| 300 ## - PHYSICAL DESCRIPTION | |
| Extent | 1 online resource (xiv, 419 pages) : |
| Other physical details | digital, PDF file(s). |
| 336 ## - Content Type (R) | |
| Content type term (R) | text |
| Content type code (R) | txt |
| Source (NR) | rdacontent |
| 337 ## - Media Type (R) | |
| Media type term (R) | computer |
| Media type code (R) | c |
| Source (NR) | rdamedia |
| 338 ## - Carrier Type (R) | |
| Carrier type term (R) | online resource |
| Carrier type code (R) | cr |
| Source (NR) | rdacarrier |
| 500 ## - GENERAL NOTE | |
| General note | Title from publisher's bibliographic system (viewed on 05 Oct 2015). |
| 505 0# - FORMATTED CONTENTS NOTE | |
| Formatted contents note | Humanization of recombinant antibodies / José W. Saldanha -- Immunogenicity assessment of antibody therapeutics / Philippe Stas [and others] -- In vitro screening for antibody immunogenicity / Frank J. Carr and Matthew B. Baker -- Antibody libraries from naïve V gene sources / Gerald Beste and David Lowe -- Antibodies from IgM libraries / Stefan Knackmuss and Vera Molkenthin -- Generation and screening of synthetic human combinatorial antibody library HuCAL GOLD / Ingo M. Klagge -- Therapeutic antibodies from XenoMouse transgenic mice / Aya Jakobovits -- VelocImmune : immunoglobulin variable region humanized mice / Andrew Murphy -- Mechanisms of tumour cell killing by therapeutic antibodies / Ross Stewart and Carl Webster -- Optimization of Fc domains to enhance antibody therapeutics / Greg A. Lazar and Aaron K. Chamberlain -- Glycoengineered therapeutic antibodies / Peter Brünker, Peter Sondermann, and Pablo Umaña -- Monoclonal antibodies for the delivery of cytotoxic drugs / David J. King. |
| 505 0# - FORMATTED CONTENTS NOTE | |
| Formatted contents note | Immunotherapy with radio-immune conjugates / Christina A. Kousparou and Agamemnon A. Epenetos -- Immunotherapeutic antibody fusion proteins / Nigel S. Courtenay-Luck and David Jones -- Alternative antibody formats / Fabrice Le Gall and Melvyn Little -- Single-domain antibodies / Serge Muyldermans, Gholamreza Hassanzadeh Ghassabeh, and Dirk Saerens -- Engineering of non-CDR loops in immunoglobulin domains / Florian Rüker and Gordana Wozniak-Knopp -- Alternative scaffolds : expanding the options of antibodies / Andreas Plückthun -- Polymer fusions to increase antibody half-lives : PEGylation and other modifications / Sam P. Heywood and David P. Humphreys -- Extending antibody half-lives with albumin / Jan Terje Andersen and Inger Sandlie -- A stem cell-based platform for the discovery and development of antitumor therapeutic antibodies to novel targets / Jennie P. Mather [and others] -- Antibody directed enzyme prodrug therapy (ADEPT) / Helen L. Lowe [and others] -- Immune privilege and tolerance -- therapeutic antibody approaches / Daron Forman [and others] -- Antibody therapeutics : business achievements and business outlook / Christophe Bourrilly. |
| 520 ## - SUMMARY, ETC. | |
| Summary, etc | Recombinant Antibodies for Immunotherapy provides a comprehensive overview of the field of monoclonal antibodies (mAbs), a market that has grown tremendously in recent years. Twenty-five articles by experienced and innovative authors cover the isolation of specific human mAbs, humanization, immunogenicity, technologies for improving efficacy, 'arming' mAbs, novel alternative Ab constructs, increasing half-lives, alternative concepts employing non-immunoglobulin scaffolds, novel therapeutic approaches, a market analysis of therapeutic mAbs, and future developments in the field. The concepts and technologies are illustrated by examples of recombinant antibodies being used in the clinic or in development. This book will appeal to both newcomers and experienced scientists in the field, biology and biotechnology students, research and development departments in the pharmaceutical industry, medical researchers, clinicians, and biotechnology investors. |
| 650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name as entry element | Monoclonal antibodies |
| General subdivision | Therapeutic use. |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Little, Melvyn, |
| Dates associated with a name | 1945- |
| Relator term | editor. |
| 776 08 - ADDITIONAL PHYSICAL FORM ENTRY | |
| Display text | Print version: |
| International Standard Book Number | 9780521887328 |
| 856 40 - ELECTRONIC LOCATION AND ACCESS | |
| Uniform Resource Identifier | <a href="https://doi.org/10.1017/CBO9780511596773">https://doi.org/10.1017/CBO9780511596773</a> |
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