Molecular chaperones and cell signalling / (Record no. 521763)
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| 000 -LEADER | |
|---|---|
| fixed length control field | 03822nam a22003618i 4500 |
| 001 - CONTROL NUMBER | |
| control field | CR9780511546310 |
| 003 - CONTROL NUMBER IDENTIFIER | |
| control field | UkCbUP |
| 005 - DATE AND TIME OF LATEST TRANSACTION | |
| control field | 20200124160319.0 |
| 006 - FIXED-LENGTH DATA ELEMENTS--ADDITIONAL MATERIAL CHARACTERISTICS--GENERAL INFORMATION | |
| fixed length control field | m|||||o||d|||||||| |
| 007 - PHYSICAL DESCRIPTION FIXED FIELD--GENERAL INFORMATION | |
| fixed length control field | cr|||||||||||| |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION | |
| fixed length control field | 090508s2005||||enk o ||1 0|eng|d |
| 020 ## - INTERNATIONAL STANDARD BOOK NUMBER | |
| International Standard Book Number | 9780511546310 (ebook) |
| 020 ## - INTERNATIONAL STANDARD BOOK NUMBER | |
| Cancelled/invalid ISBN | 9780521836548 (hardback) |
| 020 ## - INTERNATIONAL STANDARD BOOK NUMBER | |
| Cancelled/invalid ISBN | 9780521177474 (paperback) |
| 040 ## - CATALOGING SOURCE | |
| Original cataloging agency | UkCbUP |
| Language of cataloging | eng |
| Description conventions | rda |
| Transcribing agency | UkCbUP |
| 050 00 - LIBRARY OF CONGRESS CALL NUMBER | |
| Classification number | QP552.M64 |
| Item number | M64 2005 |
| 082 00 - DEWEY DECIMAL CLASSIFICATION NUMBER | |
| Classification number | 572/.645 |
| Edition number | 22 |
| 245 00 - TITLE STATEMENT | |
| Title | Molecular chaperones and cell signalling / |
| Statement of responsibility, etc | edited by Brian Henderson, A. Graham Pockley. |
| 246 3# - VARYING FORM OF TITLE | |
| Title proper/short title | Molecular Chaperones & Cell Signalling |
| 264 #1 - Production, Publication, Distribution, Manufacture, and Copyright Notice (R) | |
| Place of production, publication, distribution, manufacture (R) | Cambridge : |
| Name of producer, publisher, distributor, manufacturer (R) | Cambridge University Press, |
| Date of production, publication, distribution, manufacture, or copyright notice | 2005. |
| 300 ## - PHYSICAL DESCRIPTION | |
| Extent | 1 online resource (xiv, 330 pages) : |
| Other physical details | digital, PDF file(s). |
| 336 ## - Content Type (R) | |
| Content type term (R) | text |
| Content type code (R) | txt |
| Source (NR) | rdacontent |
| 337 ## - Media Type (R) | |
| Media type term (R) | computer |
| Media type code (R) | c |
| Source (NR) | rdamedia |
| 338 ## - Carrier Type (R) | |
| Carrier type term (R) | online resource |
| Carrier type code (R) | cr |
| Source (NR) | rdacarrier |
| 500 ## - GENERAL NOTE | |
| General note | Title from publisher's bibliographic system (viewed on 05 Oct 2015). |
| 505 0# - FORMATTED CONTENTS NOTE | |
| Formatted contents note | Chaperone function / R.J. Ellis -- Intracellular disposition of mitochondrial molecular chaperones / R.S. Gupta [and others] -- Novel pathways of protein secretion / G. Chimini, A. Rubartelli -- Moonlighting proteins / C.J. Jeffery -- Molecular chaperones / B. Henderson, A. Shamaei-Tousi -- Cell-cell signalling properties of the chaperonins / A.R.M. Coates -- Toll-like receptor-dependent activation of antigen presenting cells by Hsp60, Hsp70 and Gp96 / R.M. Vabulas, H. Wagner -- Regulation of signal transduction by intracellular and extracellular Hsp70 / A. Asea, S. Calderwood -- Hsp72 and cell signalling / M.Y. Sherman -- Heat shock proteins, their cell surface receptors and effect on the immune system / T. Lehner [and others] -- Molecular chaperone-cytokine interactions at the transcriptional level / A. Stephanou, D.S. Latchman -- Heat shock protein release and naturally-occurring exogenous heat shock proteins / J. Frostegård, A.G. Pockley -- Hsp27 as an anti-inflammatory protein / K. Laudanski, A. De, C. Miller-Graziano -- Bip, a negative immune regulator involved in rheumatoid arthritis / V.M. Corrigal, G.S. Panayi -- Neuroendocrine aspects of the molecular chaperones ADNF and ADNP / I. Gozes [and others] -- Heat shock proteins regulate by both molecular and network cross-reactivity / F.J. Quintana, I.R. Cohen -- Heat shock protein fusions / L. Mizzen, J. Neefe -- Molecular chaperones as inducers of tumour immunity / P.P. Banerjee, Z. Li -- Gazing into the crystal ball / L. Hightower. |
| 520 ## - SUMMARY, ETC. | |
| Summary, etc | Originally published in 2005, this book reviews understanding of the biological roles of extracellular molecular chaperones. It provides an overview of the structure and function of molecular chaperones, their role in the cellular response to stress and their disposition within the cell. It also questions the basic paradigm of molecular chaperone biology - that these proteins are first and foremost protein-folding molecules. Paradigms of protein secretion are reviewed and the evolving concept of proteins (such as molecular chaperones) as multi-functional molecules for which the term 'moonlighting proteins' has been introduced is discussed. The role of exogenous molecular chaperones as cell regulators is examined and the physiological and pathophysiological role that molecular chaperones play is described. In the final section, the potential therapeutic use of molecular chaperones is described and the final chapter asks the question - what does the future hold for the extracellular biology of molecular chaperones? |
| 650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name as entry element | Molecular chaperones. |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Henderson, Brian |
| Titles and other words associated with a name | (Professor), |
| Relator term | editor. |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Pockley, A. Graham |
| Fuller form of name | (Alan Graham), |
| Dates associated with a name | 1960- |
| Relator term | editor. |
| 776 08 - ADDITIONAL PHYSICAL FORM ENTRY | |
| Display text | Print version: |
| International Standard Book Number | 9780521836548 |
| 856 40 - ELECTRONIC LOCATION AND ACCESS | |
| Uniform Resource Identifier | <a href="https://doi.org/10.1017/CBO9780511546310">https://doi.org/10.1017/CBO9780511546310</a> |
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