TY - BOOK AU - Broom,Neil D. AU - Thambyah,Ashvin TI - The soft-hard tissue junction: structure, mechanics and function SN - 9781316481042 (ebook) AV - QP552.C42 B76 2019 U1 - 571.6 23 PY - 2019/// CY - Cambridge PB - Cambridge University Press KW - Cell adhesion molecules N1 - Title from publisher's bibliographic system (viewed on 15 Nov 2018) N2 - Richly illustrated throughout with actual tissue images, this innovative book shows that the soft-hard tissue junction is best understood in a biomechanical context. The authors describe their pioneering experimental methods, providing an essential structure-function framework for computational modelling, and thereby encouraging the development of more realistic, predictive models of this important tissue junction. Covering the three main musculoskeletal junctions of cartilage-bone, disc-vertebra, and ligament/tendon-bone, the relevant soft tissues are examined with respect to both their own inherent structure and their mode of integration with the hard tissue. The soft-hard tissue interface is explored with a focus on structural damage resulting from overloading, and its associated pathologies. Adopting a multiscale approach, ranging in structural resolution from the macro to fibril levels, this is a must-have guide to the field and an ideal resource for researchers seeking new and creative approaches for studying the joint and spine tissues UR - https://doi.org/10.1017/9781316481042 ER -