TY  - BOOK
AU  - Pinedo,H.M.
AU  - Giaccone,Giuseppe
TI  - Drug resistance in the treatment of cancer
T2  - Cancer, clinical science in practice
SN  - 9780511526992 (ebook)
AV  - RC271.C5 D7778 1998
U1  - 616.99/4061 21
PY  - 1998///
CY  - Cambridge
PB  - Cambridge University Press
KW  - Drug resistance in cancer cells
N1  - Title from publisher's bibliographic system (viewed on 05 Oct 2015)
N2  - The development of drug-resistant cancers is considered to be the most significant obstacle to the cure of cancer today. Nearly half of all patients with cancer suffer from tumours that are intrinsically resistant to chemotherapy, and most of the remaining half develop drug resistance during the course of their treatment. This book reviews the mechanisms and clinical implications of drug resistance in cancer with unrivalled authority. Chapters cover topics of current clinical concern, including multiple drug resistance and its reversal, topoisomerase drugs, apoptosis, dose intensity and escalation, gene therapy and haematopoietic support. The authors are among the leading clinicians and investigators in the field. These authoritative volumes in this series are intended for a wide audience of clinicians and researchers with an interest in the applications of biomedical science to the understanding and management of cancer
UR  - https://doi.org/10.1017/CBO9780511526992
ER  -