TY - BOOK AU - Savage,Caroline O.S. AU - Pearson,Jeremy D. TI - Immunological aspects of the vascular endothelium T2 - Cambridge reviews in clinical immunology SN - 9780511752629 (ebook) AV - RC694.5.I53 I48 1995 U1 - 616.13/079 20 PY - 1995/// CY - Cambridge PB - Cambridge University Press KW - Vascular endothelium KW - Immunology KW - Inflammation KW - Pathophysiology N1 - Title from publisher's bibliographic system (viewed on 05 Oct 2015) N2 - Originally published in 1995, this volume looks at the functioning of the vascular endothelium, and the diseases and tissue injury that arise as a result of inflammation and immunological responses. The vascular endothelium is a metabolically highly active layer of cells lining all blood vessel walls. Through its interactions with leucocytes and other mediators, it is central to the development of inflammatory foci and to lymphocyte trafficking around the body. Tissue injury may arise here as a result of abnormal inflammatory or immune responses. The potential for such injury to contribute to autoimmune disease is discussed in this book, particularly in relation to autoimmune vascular disease of the renal, rheumatological and neurological systems, as well as in organ transplantation. UR - https://doi.org/10.1017/CBO9780511752629 ER -