TY  - BOOK
AU  - Bellamy,Richard
TI  - Susceptibility to infectious diseases: the importance of host genetics 
T2  - Advances in molecular and cellular microbiology
SN  - 9780511546235 (ebook)
AV  - RB153 .S875 2004
U1  - 616.9/0442 21
PY  - 2004///
CY  - Cambridge
PB  - Cambridge University Press
KW  - Disease susceptibility
KW  - Infection
KW  - Host-parasite relationships
KW  - Genetic aspects
KW  - Medical genetics
N1  - Title from publisher's bibliographic system (viewed on 05 Oct 2015); 1; Introduction; Richard Bellamy --; 2; Application of genetic epidemiology to dissecting host susceptibility/resistance to infection illustrated with the study of common mycobacterial infections; Alexandre Alcais and Laurent Abel --; 3; The diverse genetic basis of immunodeficiencies; Mauno Vihinen --; 4; Genetic diversity in the major histocompatibility complex and the immune response to infectious diseases; Leland J. Yee and Mark R. Thursz --; 5; The cystic fibrosis transmembrane conductance regulator; Alan W. Cuthbert --; 6; The influence of inherited traits on malaria infection; David J. Roberts, Tyler Harris and Thomas Williams
N2  - In the last fifteen years, substantial progress has been made in identifying why some people are particularly susceptible to specific infectious diseases. Extensive evidence has accumulated that host genes are important determinants of the outcome of infection for many common pathogens. This book summarises advances that have been made in understanding the complexity of host genetic susceptibility. The diseases covered include those of great public health importance such as malaria and HIV, and those of topical interest such as Creutzfeldt-Jakob disease. Many different techniques have been used to identify host genes involved in infectious disease susceptibility. Each chapter describes how these discoveries were made and the book is therefore useful to anyone planning genetic studies on a multi-factorial disease, regardless of whether it has an infectious etiology
UR  - https://doi.org/10.1017/CBO9780511546235
ER  -