TY - BOOK AU - Craddock,Valda M. TI - Cancer of the esophagus: approaches to the etiology T2 - Cambridge monographs on cancer research SN - 9780511759925 (ebook) AV - RC280.E8 C7 1993 U1 - 616.99/432 20 PY - 1993/// CY - Cambridge PB - Cambridge University Press KW - Esophagus KW - Cancer KW - Etiology N1 - Title from publisher's bibliographic system (viewed on 05 Oct 2015) N2 - The book deals briefly with the normal structure, functioning and biochemistry of the esophagus and with the histological and genetic changes accompanying the development of esophageal cancer in humans and animals. Factors implicated in causing esophageal cancer are described in relation to its very dramatic epidemiology. Thus dietary deficiencies and consumption of foods contaminated by Fusaria mycotoxins are discussed in connection with the extremely high incidence of the disease in certain sharply demarcated regions in China and South Africa, and alcohol and tobacco use are discussed in relation to the epidemiology in Europe and USA. Other hazards mentioned include opium in Iran, betel nut in Asia and bracken in Japan. The sole group of chemicals known to be very potent esophageal carcinogens in animal experiments, the nitrosamines, are described especially in terms of the widespread human exposure UR - https://doi.org/10.1017/CBO9780511759925 ER -