TY - BOOK AU - Cohen,Jeffrey A. AU - Rudick,Richard A. TI - Multiple sclerosis therapeutics SN - 9781139023986 (ebook) AV - RC377 .M864 2011 U1 - 616.8/34 23 PY - 2011/// CY - Cambridge PB - Cambridge University Press KW - Multiple sclerosis N1 - Title from publisher's bibliographic system (viewed on 05 Oct 2015); Part I. Introduction; Part II. Clinical Trial Methodology; Part III. Clinical Trials of Multiple Sclerosis Therapies; Part IV. Therapy in Clinical Practice N2 - This book comprehensively reviews the current state of clinical trial methods in multiple sclerosis treatment, providing investigators, sponsors and specialists with current knowledge of outcome measures and study designs for disease and symptom management. The status of the rapidly evolving field of disease-modifying drugs is presented, with emphasis on the most promising therapies currently being tested. Experts discuss disease and symptom management for MS subtypes, including neuromyelitis optica and pediatric MS. In addition, key scientific advances in MS pathology, genetics, immunology and epidemiology are presented. The fourth edition has been extensively revised, featuring more than 50% new material. All chapters have been substantially updated to provide current information on rapidly evolving topics and this volume contains 15 new chapters, reflecting the growth of the field in recent years. This book is an essential reference for practitioners caring for MS patients, investigators planning or conducting clinical trials, and clinical trial sponsors UR - https://doi.org/10.1017/CBO9781139023986 ER -