TY  - BOOK
AU  - Appasani,Krishnarao
TI  - Epigenomics, from chromatin biology to therapeutics
SN  - 9780511777271 (ebook)
AV  - QH450 .E66 2012
U1  - 572.8/65 23
PY  - 2012///
CY  - Cambridge
PB  - Cambridge University Press
KW  - Epigenetics
KW  - Gene expression
N1  - Title from publisher's bibliographic system (viewed on 05 Oct 2015)
N2  - Understanding mechanisms of gene regulation that are independent of the DNA sequence itself - epigenetics - has the potential to overthrow long-held views on central topics in biology, such as the biology of disease or the evolution of species. High throughput technologies reveal epigenetic mechanisms at a genome-wide level, giving rise to epigenomics as a new discipline with a distinct set of research questions and methods. Leading experts from academia, the biotechnology and pharmaceutical industries explain the role of epigenomics in a wide range of contexts, covering basic chromatin biology, imprinting at a genome-wide level, and epigenomics in disease biology and epidemiology. Details on assays and sequencing technology serve as an up-to-date overview of the available technological tool kit. A reliable guide for newcomers to the field as well as experienced scientists, this is a unique resource for anyone interested in applying the power of twenty-first-century genomics to epigenetic studies
UR  - https://doi.org/10.1017/CBO9780511777271
ER  -