TY  - BOOK
AU  - Mansour,Tag E.
AU  - Mansour,Joan MacKinnon
TI  - Chemotherapeutic targets in parasites: contemporary strategies 
SN  - 9780511546440 (ebook)
AV  - RM412 .M365 2002
U1  - 616.9/6061 21
PY  - 2002///
CY  - Cambridge
PB  - Cambridge University Press
KW  - Antiparasitic agents
KW  - Parasitic diseases
KW  - Chemotherapy
N1  - Title from publisher's bibliographic system (viewed on 05 Oct 2015)
N2  - Parasitic infections are the most prevalent of human diseases, and researchers continue to face the challenge of designing drugs to successfully counteract them. Chemotherapeutic Targets in Parasites analyzes the critical metabolic reactions and structural features essential for parasite survival, and advocates the latest molecular strategies with which to identify effective antiparasitic agents. An introduction to the early development of parasite chemotherapy is followed by an overview of biophysical techniques and genomic and proteomic analysis. Several chapters are devoted to specific types of chemotherapeutic agents and their targets in malaria, trypanosomes, leishmania and amitochondrial protists. Chapters on helminths include metabolic, neuromuscular, microtubular and tegumental targets. Emphasized throughout is the design of more selective and less toxic drugs than in the past. This book will be especially relevant to medical and clinical researchers and to graduate students in parasitology, pharmacology, medicine, microbiology, and biochemistry
UR  - https://doi.org/10.1017/CBO9780511546440
ER  -