TY  - BOOK
AU  - Pfister,David
AU  - Nicoud,Lucrèce
AU  - Morbidelli,Massimo
TI  - Continuous biopharmaceutical processes: chromatography, bioconjugation, and protein stability 
T2  - Cambridge series in chemical engineering
SN  - 9781108332897 (ebook)
AV  - RS431.P75 P45 2018
U1  - 615.7 23
PY  - 2018///
CY  - Cambridge
PB  - Cambridge University Press
KW  - Protein drugs
KW  - Pharmaceutical technology
N1  - Title from publisher's bibliographic system (viewed on 24 Sep 2018); Introduction to biopharmaceutical processes -- Fundamentals of protein chromatography -- Counter-current separation processes -- Counter-current chromatography for the capture step -- Counter-current chromatography for the polishing steps -- Protein conjugation -- Protein aggregation in biopharmaceutical processes
N2  - This innovative reference provides a coherent and critical view on the potential benefits of a transition from batch to continuous processes in the biopharmaceutical industry, with the main focus on chromatography. It also covers the key topics of protein stability and protein conjugation, addressing the chemical reaction and purification aspects together with their integration. This book offers a fine balance between theoretical modelling and illustrative case studies, between fundamental concepts and applied examples from the academic and industrial literature. Scientists interested in the design of biopharmaceutical processes will find useful practical methodologies, in particular for single-column and multi-column chromatographic processes
UR  - https://doi.org/10.1017/9781108332897
ER  -