Enzyme structure and mechanism /
Alan Fersht.
- 2nd ed.
- W.H. Freeman, c1985.
- xxi, 475 p. : ill. ; 25 cm.
Includes bibliographies and index.
Contents: The three-dimensional structure of enzymes -- Chemical catalysis -- The basic equations of enzyme kinetics -- Management and magnitude of enzymatic rate constants -- The pH dependence of enzyme catalysis -- Practical kinetics -- Detection of intermediates in reactions by kinetics -- Stereochemistry of enzymatic reactions -- Active-site-directed and enzyme-activated irreversible inhibitors: "affinity labels" and "suicide inhibitors" -- Cooperative ligand binding, allosteric interactions, and regulation -- Forces between molecules, and enzyme-substrate binding energies -- Enzyme-substrate complementarity and the use of binding energy in catalysis -- Specificity and editing mechanisms -- Genetic engineering and enzymology: protein engineering -- Structures and mechanisms of selected enzymes.
0716716143 0716716151 (pbk.)
84004172
Enzymes. Enzymes.
ბიოლოგია ბიოქიმია ენზიმები - სტრუქტურა და მექანიზმი ენზიმოლოგია