TY  - BOOK
AU  - Holmes,Frederic Lawrence
AU  - Summers,William C.
TI  - Reconceiving the gene: Seymour Benzer's adventures in phage genetics 
SN  - 9780300129700 (electronic bk.)
AV  - QH429.2.B46 H65 2006eb
U1  - 576.5092B 22
PY  - 2006///
CY  - New Haven
PB  - Yale University Press
KW  - Benzer, Seymour.
KW  - Geneticists
KW  - United States
KW  - Biography
KW  - Bacteriophages
KW  - Genetics
KW  - Viral genetics
KW  - History
KW  - Bacteriophage T4
KW  - genetics
KW  - Genetics, Microbial
KW  - Chromosome Mapping
KW  - Genome, Bacterial
KW  - SCIENCE
KW  - Life Sciences
KW  - Genetics & Genomics
KW  - bisacsh
KW  - BIOGRAPHY & AUTOBIOGRAPHY
KW  - Science & Technology
KW  - Genetica
KW  - gtt
KW  - Microbiologie
KW  - Bacteriofagen
KW  - გენეტიკა--
KW  - ბაქტერიოფაგები
KW  - Electronic books
N1  - Includes bibliographical references (p. [303]-329) and index; Classical mendelian genetics -- Genetics and the phage biologists -- The physicist becomes a phage biologist -- To Paris and back -- Teaching and research at Purdue -- Entering the rII region -- Crossing into the fine structure -- Is gene a dirty word? -- The survival of the "gene."
N2  - A fascinating and detailed chronicle, "Reconceptualizing the Gene" relates how, between 1954 and 1961, the biologist Seymour Benzer mapped the fine structure of the rII region of the genome of the bacterial virus known as phage T4. Benzer's accomplishments and discoveries are widely recognized as a tipping point in mid-twentieth-century molecular biology when the nature of the gene was recast in molecular terms. More often than any other individual, he is considered to have led geneticists from the classical gene into the molecular age. Drawing on Benzer's remarkably complete record of his experiments, his correspondence, and published sources, Frederic Lawrence Holmes reconstructs how the former physicist initiated his work in phage biology, and how he accomplished his landmark investigation. The book follows Benzer's investigative pathway as his research unfolded and shifted, and as he adapted to opportunities or disappointments as they arose. The story of Benzer's creativity as a researcher is a fascinating story that also reveals intriguing aspects common to the scientific enterprise
UR  - http://search.ebscohost.com/login.aspx?direct=true&scope=site&db=nlebk&db=nlabk&AN=187917
ER  -