Hemochromatosis : genetics, pathophysiology, diagnosis and treatment / edited by James C. Barton and Corwin Q. Edwards.

Title from publisher's bibliographic system (viewed on 05 Oct 2015).

pt. 1. Introduction to hemochromatosis -- pt. 2. Genetics of hemochromatosis -- pt. 3. Metal absorption and metabolism in hemochromatosis -- pt. 4. Diagnostic techniques for iron overload -- pt. 5. Complications of iron overload -- pt. 6. Therapy of hemochromatosis and iron overload -- pt. 7. Infections and immunity in hemochromatosis -- pt. 8. Hemochromatosis heterozygotes -- pt. 9. Relationship of hemochromatosis to other disorders -- pt. 10. Animals models of hemochromatosis and iron overload -- pt. 11. Screening for hemochromatosis -- pt. 12. Hemochromatosis: societal and ethical issues -- pt. 13. Final issues.

Once thought rare, hemochromatosis is now acknowledged as one of the commonest inherited disorders, affecting one in two hundred people of western Caucasian descent. It is estimated to affect over one million people in the USA alone. This is the most comprehensive clinical reference yet on hemochromatosis. The international author team includes specialists in internal medicine, hematology, hepatology, genetics, biochemistry and molecular biology, and the contents cover all aspects of pathophysiology, epidemiology, diagnosis and treatment. The latest developments in the genetics of the disorder are well explained, and there are sections on screening, diagnostic techniques, and clinical complications. Social and ethical issues are also considered. Highly illustrated, up-to-date and authoritative, this is the definitive resource for all clinicians involved in the management of hemochromatosis, and will also be invaluable to scientists interested in iron metabolism and iron overload.