Drugs - Real World Outcomes targets original research and definitive reviews regarding the use of real-world data to evaluate health outcomes and inform healthcare decision-making on drugs, devices and other interventions in clinical practice. The journal includes, but is not limited to, the following research areas: Using registries/databases/health records and other non-selected observational datasets to investigate: drug use and treatment outcomes prescription patterns drug safety signals adherence to treatment guidelines benefit : risk profiles comparative effectiveness economic analyses including cost-of-illness Data-driven research methodologies, including the capture, curation, search, sharing, analysis and interpretation of ‘big data’ Techniques and approaches to optimise real-world modelling. Additional enhanced features (including slide sets, videos and animations) can be published with articles; these are designed to increase the visibility,readership and educational value of the journal’s content. In addition, articles published in Drugs - Real World Outcomes may be accompanied by plain language summaries to assist readers in understanding important medical advances.