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Principles of psychiatric genetics / edited by John I. Nurnberger Jr., Wade H. Berrettini.

Contributor(s): Material type: TextTextPublisher: Cambridge : Cambridge University Press, 2012Description: 1 online resource (xii, 402 pages) : digital, PDF file(s)Content type:
  • text
Media type:
  • computer
Carrier type:
  • online resource
ISBN:
  • 9781139025997 (ebook)
Subject(s): Additional physical formats: Print version: : No titleDDC classification:
  • 616.89/042 23
LOC classification:
  • RC455.4.G4 P75 2012
Online resources:
Contents:
Contribution of genetic epidemiology to our understanding of psychiatric disorders / Kathleen Ries Merikangas, Anibal Cravchik -- A basic overview of contemporary human genetic analysis strategies / Ondrej Libiger, Nicholas J. Schork -- DNA methods / David W. Craig -- In silico analysis strategies and resources for psychiatric genetics research / Ali Torkamani, Trygve Bakken, Nicholas J. Schork -- Gene expression studies in psychiatric disorders / Alexander B. Niculescu, III -- Pharmacogenetics in psychiatry / Falk W. Lohoff -- Functional validation of candidate genetic susceptibility factors for major mental illnesses / Akira Sawa [and others] -- Epigenetic mechanisms in drug addiction and depression / William Renthal, Eric J. Nestler -- Panic disorder / Ardesheer Talati, Myrna M. Weissman.
The genetics of phobic disorders and generalized anxiety disorder / Raymond R. Crowe -- Genetic contributions to obsessive-compulsive disorder (OCD) and OCD-related disorders / Dennis L. Murphy [and others] -- Post-traumatic stress disorder / Michael J. Lyons, Tyler Zink, Karestan C. Koenen -- Antisocial behavior : gene-environment interplay / Laura A. Baker [and others] -- Learning disabilities / Shelley D. Smith -- Attention-deficit hyperactivity disorder / Josephine Elia [and others] -- Autism and autism spectrum disorders / Daniel H. Geschwind, Maricela Alarcon -- The genetics of bipolar disorder / John R. Kelsoe -- The genetics of major depression / James B. Potash -- The genetics of schizophrenia / Hugh M.D. Gurling, Andrew McQuillin -- The genetics of anorexia and bulimia nervosa / Andrew W. Bergen, Jennifer Wessel, Walter H. Kaye -- Genetics and common human obesity / R. Arlen Price -- Alcoholism / Howard J. Edenberg -- Nicotine dependence / Sarah M. Hartz, Laura J. Bierut -- Human molecular genetics of opioid addiction / Mary Jeanne Kreek [and others] -- Genetics of stimulant dependence / Joseph F. Cubells, Yi-Lang Tang -- Genetics of personality disorders / C. Robert Cloninger -- Ethical issues in behavioral genetics / Stephen H. Dinwiddie, Jinger Hoop, Elliot Gershon -- Genetics of Tourette syndrome and related disorders / Maria G. Motlagh, Thomas V. Fernandez, James F. Leckman -- Endophenotypes in psychiatric genetics / Andrew C. Chen, Madhavi Rangaswamy, Bernice Porjesz -- Developmental disorders / Craig A. Erickson, Khendra I. Peay, Christopher J. McDougle -- Alzheimer's disease / Carlos Cruchaga, John S.K. Kauwe, Alison M. Goate.
Summary: Disorders of behavior represent some of the most common and disabling diseases affecting humankind; however, despite their worldwide distribution, genetic influences on these illnesses are often overlooked by families and mental health professionals. Psychiatric genetics is a rapidly advancing field, elucidating the varied roles of specific genes and their interactions in brain development and dysregulation. Principles of Psychiatric Genetics includes 22 disorder-based chapters covering, amongst other conditions, schizophrenia, mood disorders, anxiety disorders, Alzheimer's disease, learning and developmental disorders, eating disorders and personality disorders. Supporting chapters focus on issues of genetic epidemiology, molecular and statistical methods, pharmacogenetics, epigenetics, gene expression studies, online genetic databases and ethical issues. Written by an international team of contributors, and fully updated with the latest results from genome-wide association studies, this comprehensive text is an indispensable reference for psychiatrists, neurologists, psychologists and anyone involved in psychiatric genetic studies.
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Title from publisher's bibliographic system (viewed on 05 Oct 2015).

Contribution of genetic epidemiology to our understanding of psychiatric disorders / Kathleen Ries Merikangas, Anibal Cravchik -- A basic overview of contemporary human genetic analysis strategies / Ondrej Libiger, Nicholas J. Schork -- DNA methods / David W. Craig -- In silico analysis strategies and resources for psychiatric genetics research / Ali Torkamani, Trygve Bakken, Nicholas J. Schork -- Gene expression studies in psychiatric disorders / Alexander B. Niculescu, III -- Pharmacogenetics in psychiatry / Falk W. Lohoff -- Functional validation of candidate genetic susceptibility factors for major mental illnesses / Akira Sawa [and others] -- Epigenetic mechanisms in drug addiction and depression / William Renthal, Eric J. Nestler -- Panic disorder / Ardesheer Talati, Myrna M. Weissman.

The genetics of phobic disorders and generalized anxiety disorder / Raymond R. Crowe -- Genetic contributions to obsessive-compulsive disorder (OCD) and OCD-related disorders / Dennis L. Murphy [and others] -- Post-traumatic stress disorder / Michael J. Lyons, Tyler Zink, Karestan C. Koenen -- Antisocial behavior : gene-environment interplay / Laura A. Baker [and others] -- Learning disabilities / Shelley D. Smith -- Attention-deficit hyperactivity disorder / Josephine Elia [and others] -- Autism and autism spectrum disorders / Daniel H. Geschwind, Maricela Alarcon -- The genetics of bipolar disorder / John R. Kelsoe -- The genetics of major depression / James B. Potash -- The genetics of schizophrenia / Hugh M.D. Gurling, Andrew McQuillin -- The genetics of anorexia and bulimia nervosa / Andrew W. Bergen, Jennifer Wessel, Walter H. Kaye -- Genetics and common human obesity / R. Arlen Price -- Alcoholism / Howard J. Edenberg -- Nicotine dependence / Sarah M. Hartz, Laura J. Bierut -- Human molecular genetics of opioid addiction / Mary Jeanne Kreek [and others] -- Genetics of stimulant dependence / Joseph F. Cubells, Yi-Lang Tang -- Genetics of personality disorders / C. Robert Cloninger -- Ethical issues in behavioral genetics / Stephen H. Dinwiddie, Jinger Hoop, Elliot Gershon -- Genetics of Tourette syndrome and related disorders / Maria G. Motlagh, Thomas V. Fernandez, James F. Leckman -- Endophenotypes in psychiatric genetics / Andrew C. Chen, Madhavi Rangaswamy, Bernice Porjesz -- Developmental disorders / Craig A. Erickson, Khendra I. Peay, Christopher J. McDougle -- Alzheimer's disease / Carlos Cruchaga, John S.K. Kauwe, Alison M. Goate.

Disorders of behavior represent some of the most common and disabling diseases affecting humankind; however, despite their worldwide distribution, genetic influences on these illnesses are often overlooked by families and mental health professionals. Psychiatric genetics is a rapidly advancing field, elucidating the varied roles of specific genes and their interactions in brain development and dysregulation. Principles of Psychiatric Genetics includes 22 disorder-based chapters covering, amongst other conditions, schizophrenia, mood disorders, anxiety disorders, Alzheimer's disease, learning and developmental disorders, eating disorders and personality disorders. Supporting chapters focus on issues of genetic epidemiology, molecular and statistical methods, pharmacogenetics, epigenetics, gene expression studies, online genetic databases and ethical issues. Written by an international team of contributors, and fully updated with the latest results from genome-wide association studies, this comprehensive text is an indispensable reference for psychiatrists, neurologists, psychologists and anyone involved in psychiatric genetic studies.

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