000 02239nam a22003258i 4500
001 CR9781316756300
003 UkCbUP
005 20200124160208.0
006 m|||||o||d||||||||
007 cr||||||||||||
008 160301s2018||||enk o ||1 0|eng|d
020 _a9781316756300 (ebook)
020 _z9781107170377 (hardback)
020 _z9781316621462 (paperback)
040 _aUkCbUP
_beng
_erda
_cUkCbUP
050 4 _aQH440
_b.G46 2018
082 0 4 _a576.5072
_223
245 0 0 _aGenome editing and engineering :
_bfrom TALENs, ZFNs and CRISPRs to molecular surgery /
_cedited by Krishnarao Appasani ; with a foreword by George M. Church.
264 1 _aCambridge :
_bCambridge University Press,
_c2018.
300 _a1 online resource (xxix, 472 pages) :
_bdigital, PDF file(s).
336 _atext
_btxt
_2rdacontent
337 _acomputer
_bc
_2rdamedia
338 _aonline resource
_bcr
_2rdacarrier
500 _aTitle from publisher's bibliographic system (viewed on 01 Aug 2018).
520 _aRecent advances in genome editing tools using endonucleases such as TALENs, ZFNs, and CRISPRs, combined with genomic engineering technologies, have opened up a wide range of opportunities from applications in the basic sciences and disease biology research, to the potential for clinical applications and the development of new diagnostic tools. This complete guide to endonuclease-based genomic engineering gives readers a thorough understanding of this rapidly expanding field. Chapters cover the discovery, basic science, and application of these techniques, focusing particularly on their potential relevance to the treatment of cancer, and cardiovascular and immunological disease. The final section discusses the legal and ethical issues which accompany the technology. Providing authoritative coverage of the potential that genome editing and engineering have, this is an ideal reference for researchers and graduate students and those working in the biotechnology and pharmaceutical industries, as well as in a clinical setting.
650 0 _aGenetics
_xComputer simulation.
700 1 _aAppasani, Krishnarao,
_eeditor.
776 0 8 _iPrint version:
_z9781107170377
856 4 0 _uhttps://doi.org/10.1017/9781316756300
999 _c515539
_d515537