000			04299nam a22003618i 4500
001			CR9781316014707
003			UkCbUP
005			20200124160214.0
006			m|||||o||d||||||||
007			cr||||||||||||
008			140327s2015||||enk o ||1 0|eng|d
020			_a9781316014707 (ebook)
020			_z9781107082984 (hardback)
040			_aUkCbUP _beng _erda _cUkCbUP
050	0	0	_aRB113 _b.M65 2015
082	0	0	_a616.07 _223
245	0	0	_aMolecular pathology : _ba practical guide for the surgical pathologist and cytopathologist / _cedited by John M. S. Bartlett, Abeer Shaaban, Fernando Schmitt.
264		1	_aCambridge : _bCambridge University Press, _c2015.
300			_a1 online resource (xix, 396 pages) : _bdigital, PDF file(s).
336			_atext _btxt _2rdacontent
337			_acomputer _bc _2rdamedia
338			_aonline resource _bcr _2rdacarrier
500			_aTitle from publisher's bibliographic system (viewed on 01 Feb 2016).
505	8		_aMachine generated contents note: List of contributors; Preface; 1. An introduction to molecular pathology John M. S. Bartlett; 2. Molecular regulation of cellular function Marsela Braunstein and John M. S. Bartlett; 3. Practical application of molecular techniques in diagnostic histopathology and cytopathology and clinical management Abeer Shaaban and Fernando Schmitt; 4. Fluorescent and non-fluorescent in situ hybridization Jane Bayani and John M. S. Bartlett; 5. Clinical applications of the polymerase chain reaction for molecular pathology Angela B. Y. Hui, Annette D. Wong and Carlo V. Hojilla; 6. Are microarrays ready for prime time? Jane Bayani and John M. S. Bartlett; 7. Tissue microarrays Luigi Tornillo; 8. Sequencing Andrew M. K. Brown, Philipe C. Zuzarte and Paul M. Krzyzanowski; 9. Microsatellite instability in colorectal cancer Maria Sofia Fernandes, Raquel Seruca and Se;rgia Velho; 10. Mutational analysis Aaron R. Hansen, Mahadeo A. Sukhai, Hal K. Berman, Suzanne Kamel-Reid and Philippe L. Bedard; 11. Tumors of the breast Cathy B. Moelans, Petra van der Groep, Robert Kornegoor, Jelle Wesseling and Paul J. van Diest; 12. Tumors of the female genital system Adhemar Longatto Filho, Sigurd F. Lax and Bin Yang; 13. Tumours of the male urogenital system Kirsten D. Mertz and Lukas Bubendorf; 14. Tumors of the gastrointestinal system Manuel Salto-Tellez, Benedict Yan, Roseann I. Wu and Martha Bishop Pitman; 15. Soft tissue, bone and skin tumours Stamatios Theocharis and Jerzy Klijanienko; 16. Cardio-thoracic tumors Umberto Malapelle, Claudio Bellevicine, Elena Vigliar and Giancarlo Troncone; 17. Tumors of the endocrine system Sylvia L. Asa and Ozgur Mete; 18. Haematological malignancies of the lymph nodes Sarah E. Coupland and Pedro Farinha; 19. Pediatric tumors Paul Roberts, Susan Picton and Jens Stahlschmidt; 20. Serous effusions Ben Davidson; 21. Academic applications and future of molecular pathology Manuel Salto-Tellez and Benedict Yan; Index.
520			_aThis practical manual provides a comprehensive yet concise guide to state-of-the-art molecular techniques and their applications. It starts with an overview of the essential principles of molecular techniques, followed by separate chapters detailing the use of these techniques in particular tissues and organs, and describing recommended treatment plans. Each chapter covers the tests available, their advantages, limitations, and use as diagnostic and prognostic tools, with key learning points at the end of each topic. Using both histologic and cytologic samples, it discusses how to interpret test results in a pathologic context and enables trainees and practising pathologists to gain an in-depth understanding of molecular diagnostic techniques and how to incorporate them into routine diagnostic practice. Aiding the daily practice of refining diagnosis, as well as offering a didactic approach, this book is an essential reference for practising pathologists and cytopathologists as well as trainees in pathology.
650		0	_aPathology, Molecular.
650		0	_aMolecular diagnosis.
700	1		_aBartlett, John M. S., _eeditor.
700	1		_aShaaban, Abeer, _eeditor.
700	1		_aSchmitt, Fernando, _eeditor.
776	0	8	_iPrint version: _z9781107082984
856	4	0	_uhttps://doi.org/10.1017/CBO9781316014707
999			_c516107 _d516105