000			02975nam a22003978i 4500
001			CR9780511546235
003			UkCbUP
005			20200124160227.0
006			m|||||o||d||||||||
007			cr||||||||||||
008			090508s2004||||enk o ||1 0|eng|d
020			_a9780511546235 (ebook)
020			_z9780521815253 (hardback)
020			_z9780521129596 (paperback)
040			_aUkCbUP _beng _erda _cUkCbUP
050	0	0	_aRB153 _b.S875 2004
082	0	0	_a616.9/0442 _221
245	0	0	_aSusceptibility to infectious diseases : _bthe importance of host genetics / _cedited by Richard Bellamy.
264		1	_aCambridge : _bCambridge University Press, _c2004.
300			_a1 online resource (xvi, 398 pages) : _bdigital, PDF file(s).
336			_atext _btxt _2rdacontent
337			_acomputer _bc _2rdamedia
338			_aonline resource _bcr _2rdacarrier
490	1		_aAdvances in molecular and cellular microbiology ; _v4
500			_aTitle from publisher's bibliographic system (viewed on 05 Oct 2015).
505	0	0	_g1. _tIntroduction / _rRichard Bellamy -- _g2. _tApplication of genetic epidemiology to dissecting host susceptibility/resistance to infection illustrated with the study of common mycobacterial infections / _rAlexandre Alcais and Laurent Abel -- _g3. _tThe diverse genetic basis of immunodeficiencies / _rMauno Vihinen -- _g4. _tGenetic diversity in the major histocompatibility complex and the immune response to infectious diseases / _rLeland J. Yee and Mark R. Thursz -- _g5. _tThe cystic fibrosis transmembrane conductance regulator / _rAlan W. Cuthbert -- _g6. _tThe influence of inherited traits on malaria infection / _rDavid J. Roberts, Tyler Harris and Thomas Williams.
520			_aIn the last fifteen years, substantial progress has been made in identifying why some people are particularly susceptible to specific infectious diseases. Extensive evidence has accumulated that host genes are important determinants of the outcome of infection for many common pathogens. This book summarises advances that have been made in understanding the complexity of host genetic susceptibility. The diseases covered include those of great public health importance such as malaria and HIV, and those of topical interest such as Creutzfeldt-Jakob disease. Many different techniques have been used to identify host genes involved in infectious disease susceptibility. Each chapter describes how these discoveries were made and the book is therefore useful to anyone planning genetic studies on a multi-factorial disease, regardless of whether it has an infectious etiology.
650		0	_aDisease susceptibility.
650		0	_aInfection.
650		0	_aHost-parasite relationships _xGenetic aspects.
650		0	_aMedical genetics.
700	1		_aBellamy, Richard _q(Richard John), _eeditor.
776	0	8	_iPrint version: _z9780521815253
830		0	_aAdvances in molecular and cellular microbiology ; _v4.
856	4	0	_uhttps://doi.org/10.1017/CBO9780511546235
999			_c517312 _d517310