000			02151nam a22003498i 4500
001			CR9780511759925
003			UkCbUP
005			20200124160234.0
006			m|||||o||d||||||||
007			cr||||||||||||
008			100430s1993||||enk o ||1 0|eng|d
020			_a9780511759925 (ebook)
020			_z9780521373937 (hardback)
020			_z9780521102582 (paperback)
040			_aUkCbUP _beng _erda _cUkCbUP
050	0	0	_aRC280.E8 _bC7 1993
082	0	0	_a616.99/432 _220
100	1		_aCraddock, Valda M., _eauthor.
245	1	0	_aCancer of the esophagus : _bapproaches to the etiology / _cValda M. Craddock.
264		1	_aCambridge : _bCambridge University Press, _c1993.
300			_a1 online resource (xiv, 282 pages) : _bdigital, PDF file(s).
336			_atext _btxt _2rdacontent
337			_acomputer _bc _2rdamedia
338			_aonline resource _bcr _2rdacarrier
490	1		_aCambridge monographs on cancer research
500			_aTitle from publisher's bibliographic system (viewed on 05 Oct 2015).
520			_aThe book deals briefly with the normal structure, functioning and biochemistry of the esophagus and with the histological and genetic changes accompanying the development of esophageal cancer in humans and animals. Factors implicated in causing esophageal cancer are described in relation to its very dramatic epidemiology. Thus dietary deficiencies and consumption of foods contaminated by Fusaria mycotoxins are discussed in connection with the extremely high incidence of the disease in certain sharply demarcated regions in China and South Africa, and alcohol and tobacco use are discussed in relation to the epidemiology in Europe and USA. Other hazards mentioned include opium in Iran, betel nut in Asia and bracken in Japan. The sole group of chemicals known to be very potent esophageal carcinogens in animal experiments, the nitrosamines, are described especially in terms of the widespread human exposure.
650		0	_aEsophagus _xCancer _xEtiology.
776	0	8	_iPrint version: _z9780521373937
830		0	_aCambridge monographs on cancer research.
856	4	0	_uhttps://doi.org/10.1017/CBO9780511759925
999			_c517932 _d517930