000			02466nam a22003738i 4500
001			CR9780511564383
003			UkCbUP
005			20200124160238.0
006			m|||||o||d||||||||
007			cr||||||||||||
008			090518s1993||||enk o ||1 0|eng|d
020			_a9780511564383 (ebook)
020			_z9780521440059 (hardback)
020			_z9780521445801 (paperback)
040			_aUkCbUP _beng _erda _cUkCbUP
050	0	0	_aQD471 _b.B313 1993
082	0	0	_a547 _220
100	1		_aBarton, Derek H. R., _d1918-1998, _eauthor.
245	1	0	_aHalf a century of free radical chemistry / _cDerek H.R. Barton, in collaboration with Shyamal I. Parekh.
264		1	_aCambridge : _bCambridge University Press, _c1993.
300			_a1 online resource (xi, 164 pages) : _bdigital, PDF file(s).
336			_atext _btxt _2rdacontent
337			_acomputer _bc _2rdamedia
338			_aonline resource _bcr _2rdacarrier
490	1		_aLezioni lincee
500			_aTitle from publisher's bibliographic system (viewed on 05 Oct 2015).
520			_aThis book describes the experience over 25 years of the senior author with the chemistry of organic free radicals. It begins with a mechanistic study of industrial importance on the pyrolysis of chlorinated alkanes. It continues with a theory on the biosynthesis of phenolate derived alkaloids involving phenolate radical coupling. There follows 20 years of practical work to prove the theory correct, especially in the case of morphine alkaloids. The book then describes the work on nitrile photolysis (Barton reaction) which involved the invention of new radical chemistry leading to a simple synthesis of the important hormone, aldosterone. There follows a description of the invention of an important new method for the deoxygenation of biologically important molecules, especially sugars and nucleosides, using radical chemistry applied to thiocarbonyl derivatives. Some years later, in a logical extension to carboxylic acids, another new reaction was invented which provides carbon, nitrogen, oxygen and other radicals under mild conditions. A final chapter summarizes recent applications of thiocarbonyl group derived radical reactions by other authors.
650		0	_aFree radical reactions.
650		0	_aOrganic compounds _xSynthesis.
700	1		_aParekh, Shyamal I., _eauthor.
776	0	8	_iPrint version: _z9780521440059
830		0	_aLezioni lincee.
856	4	0	_uhttps://doi.org/10.1017/CBO9780511564383
999			_c518245 _d518243