000			02471nam a22003738i 4500
001			CR9780511584589
003			UkCbUP
005			20200124160244.0
006			m|||||o||d||||||||
007			cr||||||||||||
008			090612s2006||||enk o ||1 0|eng|d
020			_a9780511584589 (ebook)
020			_z9780521860925 (hardback)
020			_z9781107636989 (paperback)
040			_aUkCbUP _beng _erda _cUkCbUP
050	0	0	_aQH450 _b.B39 2006
082	0	0	_a572.8/6501519542 _222
245	0	0	_aBayesian inference for gene expression and proteomics / _cedited by Kim-Anh Do, Peter Müller, Marina Vannucci.
246	3		_aBayesian Inference for Gene Expression & Proteomics
264		1	_aCambridge : _bCambridge University Press, _c2006.
300			_a1 online resource (xviii, 437 pages) : _bdigital, PDF file(s).
336			_atext _btxt _2rdacontent
337			_acomputer _bc _2rdamedia
338			_aonline resource _bcr _2rdacarrier
500			_aTitle from publisher's bibliographic system (viewed on 05 Oct 2015).
520			_aThe interdisciplinary nature of bioinformatics presents a research challenge in integrating concepts, methods, software and multiplatform data. Although there have been rapid developments in new technology and an inundation of statistical methods for addressing other types of high-throughput data, such as proteomic profiles that arise from mass spectrometry experiments. This book discusses the development and application of Bayesian methods in the analysis of high-throughput bioinformatics data that arise from medical, in particular, cancer research, as well as molecular and structural biology. The Bayesian approach has the advantage that evidence can be easily and flexibly incorporated into statistical methods. A basic overview of the biological and technical principles behind multi-platform high-throughput experimentation is followed by expert reviews of Bayesian methodology, tools and software for single group inference, group comparisons, classification and clustering, motif discovery and regulatory networks, and Bayesian networks and gene interactions.
650		0	_aGene expression _xStatistical methods.
650		0	_aProteomics _xStatistical methods.
700	1		_aDo, Kim-Anh, _d1960- _eeditor.
700	1		_aMüller, Peter, _d1963 August 9- _eeditor.
700	1		_aVannucci, Marina, _d1966- _eeditor.
776	0	8	_iPrint version: _z9780521860925
856	4	0	_uhttps://doi.org/10.1017/CBO9780511584589
999			_c518834 _d518832