000 02551nam a22003618i 4500
001 CR9780511614736
003 UkCbUP
005 20200124160300.0
006 m|||||o||d||||||||
007 cr||||||||||||
008 090914s2005||||enk o ||1 0|eng|d
020 _a9780511614736 (ebook)
020 _z9780521841955 (hardback)
020 _z9780521603010 (paperback)
040 _aUkCbUP
_beng
_erda
_cUkCbUP
050 0 0 _aQH325
_b.D418 2005
082 0 0 _a576.8/3
_222
100 1 _aDe Duve, Christian,
_eauthor.
245 1 0 _aSingularities :
_blandmarks on the pathways of life /
_cChristian de Duve.
264 1 _aCambridge :
_bCambridge University Press,
_c2005.
300 _a1 online resource (xiv, 258 pages) :
_bdigital, PDF file(s).
336 _atext
_btxt
_2rdacontent
337 _acomputer
_bc
_2rdamedia
338 _aonline resource
_bcr
_2rdacarrier
500 _aTitle from publisher's bibliographic system (viewed on 05 Oct 2015).
505 0 _aBuilding blocks -- Homochirality -- Protometabolism -- ATP -- Electrons and protons -- Thioesters -- RNA -- Proteins -- DNA -- Membranes -- Protonmotive force -- Protometabolism revisited -- The LUCA -- The first fork -- Eukaryotes -- Oxygen -- Endosymbionts -- Multicellulars -- Homo -- Evolution -- Final comments.
520 _aErwin Schrödinger's What is Life? published 60 years ago, influenced much of the development of molecular biology. In this new book Christian De Duve, Nobel Laureate and pioneer of modern cell biology, presents a contemporary response to this classic, providing a sophisticated consideration of the key steps or bottlenecks that constrain the origins and evolution of life. De Duve surveys the entire history of life, including insights into the conditions that may have led to its emergence. He uses as landmarks the many remarkable singularities along the way, such as the single ancestry of all living beings, the universal genetic code, and the monophyletic origin of eukaryotes. The book offers a brief guided tour of biochemistry and phylogeny, from the basic molecular building blocks to the origin of humans. Each successive singularity is introduced in a sequence paralleling the hypothetical development of features and conditions on the primitive earth, explaining how and why each transition to greater complexity occurred.
650 0 _aLife
_xOrigin.
650 0 _aEvolution (Biology)
650 0 _aSingularities (Mathematics)
776 0 8 _iPrint version:
_z9780521841955
856 4 0 _uhttps://doi.org/10.1017/CBO9780511614736
999 _c520295
_d520293