000			02864nam a22003858i 4500
001			CR9780511759512
003			UkCbUP
005			20200124160300.0
006			m|||||o||d||||||||
007			cr||||||||||||
008			100430s2009||||enk o ||1 0|eng|d
020			_a9780511759512 (ebook)
020			_z9780521886529 (hardback)
020			_z9780521714020 (paperback)
040			_aUkCbUP _beng _erda _cUkCbUP
050	0	0	_aRC71.3 _b.N49 2009
082	0	0	_a616.07/5 _222
100	1		_aNewman, Thomas B., _eauthor.
245	1	0	_aEvidence-based diagnosis / _cThomas B. Newman, Michael A. Kohn.
264		1	_aCambridge : _bCambridge University Press, _c2009.
300			_a1 online resource (xiii, 295 pages) : _bdigital, PDF file(s).
336			_atext _btxt _2rdacontent
337			_acomputer _bc _2rdamedia
338			_aonline resource _bcr _2rdacarrier
500			_aTitle from publisher's bibliographic system (viewed on 05 Oct 2015).
505	0		_aIntroduction: Understanding diagnosis and diagnostic testing -- Reliability and measurement error -- Dichotomous tests -- Multilevel and continuous tests -- Critical appraisal of studies of diagnostic tests -- Screening tests -- Prognostic tests and studies -- Multiple tests and multivariable decision rules -- Quantifying treatment effects using randomized trials -- Alternatives to randomized trials for estimating treatment effects -- Understanding P-values and confidence intervals -- Challenges for evidence-based diagnosis.
520			_aEvidence-Based Diagnosis explains diagnostic, screening, and prognostic tests in clinical medicine. The authors' approach is based on many years of experience teaching physicians in a clinical research training program. Although needing only a minimum of mathematics, the quantitative discussions in this book are deeper and more rigorous than in most introductory texts. The book includes numerous worked examples and 60 problems (with answers) based on real clinical situations and journal articles. This book is a great choice for anyone looking to select, develop, or apply medical tests. Topics covered include: the diagnostic process; test reliability and accuracy; testing and treatment thresholds; critical appraisal of studies of diagnostic, screening and prognostic tests; test independence and methods of combining tests; quantifying treatment benefits using randomized trials and observational studies; Bayesian interpretation of P values and confidence intervals; challenges for evidence-based diagnosis; likelihood ratios and ROC curves.
650		0	_aDiagnosis.
650		0	_aEvidence-based medicine.
650		0	_aFunction tests (Medicine) _xEvaluation.
650		0	_aDiagnosis _xResearch.
700	1		_aKohn, Michael A., _eauthor.
776	0	8	_iPrint version: _z9780521886529
856	4	0	_uhttps://doi.org/10.1017/CBO9780511759512
999			_c520299 _d520297