000 02511nam a22003498i 4500
001 CR9780511895401
003 UkCbUP
005 20200124160308.0
006 m|||||o||d||||||||
007 cr||||||||||||
008 101122s1991||||enk o ||1 0|eng|d
020 _a9780511895401 (ebook)
020 _z9780521364812 (hardback)
020 _z9780521063319 (paperback)
040 _aUkCbUP
_beng
_erda
_cUkCbUP
050 0 0 _aQP383.25
_b.T73 1991
082 0 0 _a599/.0188
_220
100 1 _aTraub, Roger D.,
_eauthor.
245 1 0 _aNeuronal networks of the hippocampus /
_cRoger D. Traub, Richard Miles ; appendix by Lawrence S. Schulman.
264 1 _aCambridge :
_bCambridge University Press,
_c1991.
300 _a1 online resource (xviii, 281 pages) :
_bdigital, PDF file(s).
336 _atext
_btxt
_2rdacontent
337 _acomputer
_bc
_2rdamedia
338 _aonline resource
_bcr
_2rdacarrier
500 _aTitle from publisher's bibliographic system (viewed on 05 Oct 2015).
520 _aThe questions of how a large population of neurons in the brain functions, how synchronized firing of neurons is achieved, and what factors regulate how many and which neurons fire under different conditions form the central theme of this book. Using a combined experimental-theoretical approach unique in neuroscience, the authors present important techniques for the physiological reconstruction of a large biological neuronal network. They begin by discussing experimental studies of the CA3 hippocampal region in vitro, focusing on single-cell and synaptic electrophysiology, particularly the effects a single neuron exerts on its neighbours. This is followed by a description of a computer model of the system, first for individual cells then for the entire detailed network, and the model is compared with experiments under a variety of conditions. The results shed significant light into the mechanisms of epilepsy, electroencephalograms, and biological oscillations and provide an excellent test case for theories of neural networks. Researchers in neurophysiology and physiological psychology, physicians concerned with epilepsy and related disorders, and researchers in computational neuroscience will find this book an invaluable resource.
650 0 _aHippocampus (Brain)
_xComputer simulation.
650 0 _aNeural networks (Neurobiology)
700 1 _aMiles, Richard,
_d1951-
_eauthor.
776 0 8 _iPrint version:
_z9780521364812
856 4 0 _uhttps://doi.org/10.1017/CBO9780511895401
999 _c520840
_d520838