000			02723nam a22003378i 4500
001			CR9780511545849
003			UkCbUP
005			20200124160310.0
006			m|||||o||d||||||||
007			cr||||||||||||
008			090507s2006||||enk o ||1 0|eng|d
020			_a9780511545849 (ebook)
020			_z9780521853965 (hardback)
040			_aUkCbUP _beng _erda _cUkCbUP
050	0	0	_aQH450 _b.G46254 2006
082	0	0	_a572.865 _222
245	0	0	_aGene expression profiling by microarrays : _bclinical implications / _cedited by Wolf-Karsten Hofmann.
264		1	_aCambridge : _bCambridge University Press, _c2006.
300			_a1 online resource (xiv, 246 pages) : _bdigital, PDF file(s).
336			_atext _btxt _2rdacontent
337			_acomputer _bc _2rdamedia
338			_aonline resource _bcr _2rdacarrier
500			_aTitle from publisher's bibliographic system (viewed on 05 Oct 2015).
505	0		_aTechnique of microarrays : microarray platforms / Sven de Vos -- Quantitative quality control of microarray experiments : toward accurate gene expression measurements / Xujing Wang and Martin J. Hessner -- Statistical analysis of gene expression data / David A. Elashoff -- Genomic stratification in patients with heart failure / Tara A. Bullard [and others] -- Gene expression profiling for the diagnosis of acute leukemias / Torsten Haferlach [and others] -- Gene expression profiling can distinguish tumor subclasses of breast carcinomas / Ingrid A. Hedenfalk -- Gene expression profiling in lymphoid malignancies / Christof Burek [and others] -- mRNA profiling of pancreatic beta-cells : investigating mechanisms of diabetes / Leentje Van Lommel [and others] -- Prediction of response and resistance to treatment by gene expression profiling / Philipp Kiewe and Wolf-Karsten Hofmann.
520			_aMicroarray analysis is a highly efficient tool for assessing the expression of a large number of genes simultaneously, and offers a new means to classify cancer and other diseases. Gene expression profiling can also be used to predict clinical outcome and response to specific therapeutic agents. This survey spans recent applications of microarrays in clinical medicine, covering malignant disease including acute leukaemias, lymphoid malignancies and breast cancer, together with diabetes and heart disease. Investigators in oncology, pharmacology and related clinical sciences, as well as basic scientists, will value this review of a promising new diagnostic and prognostic technology.
650		0	_aGene expression.
650		0	_aMedical genetics.
700	1		_aHofmann, Wolf-Karsten, _eeditor.
776	0	8	_iPrint version: _z9780521853965
856	4	0	_uhttps://doi.org/10.1017/CBO9780511545849
999			_c521018 _d521016