000			03369nam a22003618i 4500
001			CR9780511526985
003			UkCbUP
005			20200124160311.0
006			m|||||o||d||||||||
007			cr||||||||||||
008			090407s2001||||enk o ||1 0|eng|d
020			_a9780511526985 (ebook)
020			_z9780521660297 (hardback)
040			_aUkCbUP _beng _erda _cUkCbUP
050	0	0	_aQH585.5.F56 _bC98 2001
082	0	0	_a571.6/028 _221
245	0	0	_aCytometric analysis of cell phenotype and function / _cedited by Desmond A. McCarthy and Marion G. Macey.
246	3		_aCytometric Analysis of Cell Phenotype & Function
264		1	_aCambridge : _bCambridge University Press, _c2001.
300			_a1 online resource (xvi, 413 pages) : _bdigital, PDF file(s).
336			_atext _btxt _2rdacontent
337			_acomputer _bc _2rdamedia
338			_aonline resource _bcr _2rdacarrier
500			_aTitle from publisher's bibliographic system (viewed on 05 Oct 2015).
505	0		_aPrinciples of flow cytometry / Marion G. Macey -- Introduction to the general principles of sample preparation / Desmond A. McCarthy -- Fluorescence and fluorochromes / Desmond A. McCarthy -- Data analysis in flow cytometry / Mark W. Lowdell -- Laser scanning cytometry: application to the immunophenotyping of hematological malignancies / Richard J. Clatch -- Leukoycte immunobiology / Marion G. Macey -- Immunophenotypic analysis of leukocytes in disease / Jamie D. Cavenagh, Marion G. Macey and Timothy M. Milne -- Analysis and isolation of minor cell populations / Terry Hoy -- Cell cycle, DNA and DNA ploidy analysis / Paul D. Allen and Adrian C. Newland -- Cell viability, necrosis and apoptosis / Paul D. Allen and Adrian C. Newland -- Phagocyte biology and function / Marion G. Macey -- Intracellular measures of singalling pathways / James W. Jacobberger and David W. Hedley -- Cell-cell interactions / Marion G. Macey and Mary R. Cahill -- Nucleic acids / Charles L. Goolsby -- Microbial infections / David Lloyd, David J. Mason and Marc T.E. Suller -- Leucoyte cell surface antigens / Marion G. Macey -- Recent and future developments: conclusions / Desmond A. McCarthy -- Appendix -- Index.
520			_aFlow cytometry and laser scanning cytometry are increasingly used in clinical and research settings, following improvements in instrument design and computing power and the increased availability of fluorescent agents. This book provides a comprehensive introduction to the theory and clinical applications of these techniques in the assessment of cell phenotype and function. With an emphasis on clinical relevance, the book presents the principles and potential of cytometry in the analysis of phenomena including cell-mediated cytotoxicity, metabolic burst, phagocytosis, cell-cell aggregation, receptor shedding and apoptosis. Guidance is given on data interpretation, quality control procedures, pitfalls and problems. All chapters contain detailed protocols from leading authorities in the field with extensive practical experience.
650		0	_aFlow cytometry _vHandbooks, manuals, etc.
650		0	_aCytology _vHandbooks, manuals, etc.
700	1		_aMcCarthy, Desmond A. _q(Desmond Anthony), _d1940- _eeditor.
700	1		_aMacey, Marion G., _eeditor.
776	0	8	_iPrint version: _z9780521660297
856	4	0	_uhttps://doi.org/10.1017/CBO9780511526985
999			_c521095 _d521093