000			02193nam a22003378i 4500
001			CR9780511777271
003			UkCbUP
005			20200124160315.0
006			m|||||o||d||||||||
007			cr||||||||||||
008			100514s2012||||enk o ||1 0|eng|d
020			_a9780511777271 (ebook)
020			_z9781107003828 (hardback)
020			_z9781107697836 (paperback)
040			_aUkCbUP _beng _erda _cUkCbUP
050	0	0	_aQH450 _b.E66 2012
082	0	0	_a572.8/65 _223
245	0	0	_aEpigenomics, from chromatin biology to therapeutics / _cedited by Krishnarao Appasani ; forword by Azim Surani.
264		1	_aCambridge : _bCambridge University Press, _c2012.
300			_a1 online resource (xxx, 518 pages) : _bdigital, PDF file(s).
336			_atext _btxt _2rdacontent
337			_acomputer _bc _2rdamedia
338			_aonline resource _bcr _2rdacarrier
500			_aTitle from publisher's bibliographic system (viewed on 05 Oct 2015).
520			_aUnderstanding mechanisms of gene regulation that are independent of the DNA sequence itself - epigenetics - has the potential to overthrow long-held views on central topics in biology, such as the biology of disease or the evolution of species. High throughput technologies reveal epigenetic mechanisms at a genome-wide level, giving rise to epigenomics as a new discipline with a distinct set of research questions and methods. Leading experts from academia, the biotechnology and pharmaceutical industries explain the role of epigenomics in a wide range of contexts, covering basic chromatin biology, imprinting at a genome-wide level, and epigenomics in disease biology and epidemiology. Details on assays and sequencing technology serve as an up-to-date overview of the available technological tool kit. A reliable guide for newcomers to the field as well as experienced scientists, this is a unique resource for anyone interested in applying the power of twenty-first-century genomics to epigenetic studies.
650		0	_aEpigenetics.
650		0	_aGene expression.
700	1		_aAppasani, Krishnarao, _d1959- _eeditor.
776	0	8	_iPrint version: _z9781107003828
856	4	0	_uhttps://doi.org/10.1017/CBO9780511777271
999			_c521385 _d521383