000			02728nam a22003618i 4500
001			CR9780511546341
003			UkCbUP
005			20200124160316.0
006			m|||||o||d||||||||
007			cr||||||||||||
008			090508s2002||||enk o ||1 0|eng|d
020			_a9780511546341 (ebook)
020			_z9780521590686 (hardback)
020			_z9780521021173 (paperback)
040			_aUkCbUP _beng _erda _cUkCbUP
050	0	4	_aRA793 _b.N45 2002
082	0	0	_a616.07/9 _221
100	1		_aNelson, Randy Joe, _eauthor.
245	1	0	_aSeasonal patterns of stress, immune function, and disease / _cRandy J. Nelson [and others].
246	3		_aSeasonal Patterns of Stress, Immune Function, & Disease
264		1	_aCambridge : _bCambridge University Press, _c2002.
300			_a1 online resource (xv, 291 pages) : _bdigital, PDF file(s).
336			_atext _btxt _2rdacontent
337			_acomputer _bc _2rdamedia
338			_aonline resource _bcr _2rdacarrier
500			_aTitle from publisher's bibliographic system (viewed on 05 Oct 2015).
505	0		_aSeasonality -- Immune function -- Seasonal fluctuations in disease prevalence -- Seasonal changes in immune function -- Photoperiod, melatonin, and immunity -- Energetics and immune function -- Hormonal influence on immune function -- Clinical significance of seasonal patterns of immune function and disease.
520			_aThis book presents evidence that infection is cyclical with the seasons, and that this phenomenon is mirrored in cycles of immune function. The book identifies the mechanisms by which immune systems are bolstered to counteract seasonally-recurrent stressors, such as extreme temperature reductions and food shortages. Stress, infectious diseases, autoimmune diseases, and human cancers are examined, and the role of hormones such as melatonin and glucocorticoids is considered. The book begins with an overview of seasonality, biological rhythms and photoperiodism, and basic immunology, and then discusses seasonal fluctuations in disease prevalence, immune function, and energetics and endocrinology as they relate to immune function. The clinical significance of this issue is also addressed, as such seasonal changes may play an important role in the development and treatment of infections. This first monograph to examine seasonal immune function from an interdisciplinary perspective will serve practitioners as well as advanced undergraduates and graduate students in biology, immunology, human and veterinary medicine, neuroscience, endocrinology, and zoology.
650		0	_aDiseases _xSeasonal variations.
650		0	_aImmunity.
776	0	8	_iPrint version: _z9780521590686
856	4	0	_uhttps://doi.org/10.1017/CBO9780511546341
999			_c521518 _d521516