000			03088nam a22003738i 4500
001			CR9781316257081
003			UkCbUP
005			20200124160317.0
006			m|||||o||d||||||||
007			cr||||||||||||
008			141028s2004||||enk o ||1 0|eng|d
020			_a9781316257081 (ebook)
020			_z9780521811415 (hardback)
020			_z9781107406582 (paperback)
040			_aUkCbUP _beng _erda _cUkCbUP
050	0	0	_aQP82.A36 _bA457 2004
082	0	0	_a612/.022 _222
245	0	0	_aAllostasis, homeostasis and the costs of physiological adaptation / _cedited by Jay Schulkin.
246	3		_aAllostasis, Homeostasis, & the Costs of Physiological Adaptation
264		1	_aCambridge : _bCambridge University Press, _c2004.
300			_a1 online resource (xii, 372 pages) : _bdigital, PDF file(s).
336			_atext _btxt _2rdacontent
337			_acomputer _bc _2rdamedia
338			_aonline resource _bcr _2rdacarrier
500			_aTitle from publisher's bibliographic system (viewed on 05 Oct 2015).
505	0	0	_tIntroduction / _rJay Schulkin -- _g1. _tPrinciples of allostasis : optimal design, predictive regulation, pathophysiology, and rational therapeutics / _rPeter Sterling -- _g2. _tProtective and damaging effects of the mediators of stress and adaptation : allostasis and allostatic load / _rBruce S. McEwen -- _g3. _tMerging of the homeostat theory with the concept of allostatic load / _rDavid S. Goldstein -- _g4. _tOperationalizing allostatic load / _rBurton Singer, Carol D. Ryff and Teresa Seeman -- _g5. _tDrug addiction and allostasis / _rGeorge F. Koob and Michel Le Moal -- _g6. _tAdaptive fear, allostasis, and the pathology of anxiety and depression / _rJeffrey B. Rosen and Jay Schulkin.
520			_aThe concept of homeostasis, the maintenance of the internal physiological environment of an organism within tolerable limits, is well established in medicine and physiology. In contrast, allostasis is a relatively new idea of 'viability through change'. With allostatic regulation by cephalic involvement, the body adapts to potentially diverse and dangerous situations through the activation of neural, hormonal, or immunological mechanisms. Allostasis explains how regulatory events maintain organismic viability, or not, in diverse contexts with varying set points of bodily needs and competing motivations. This 2005 book introduces the concept of allostasis and sets it alongside traditional views of homeostasis. It addresses basic regulatory systems and examines the behavior of bodily regulation under duress. The basic concepts of physiological homeostasis are integrated with disorders like depression, stress, anxiety and addiction. It will therefore appeal to graduate students, medical students and researchers working in physiology, epidemiology, endocrinology, neuroendocrinology, neuroscience, and psychology.
650		0	_aAllostasis.
650		0	_aHomeostasis.
650		0	_aAdaptation (Physiology)
700	1		_aSchulkin, Jay, _eeditor.
776	0	8	_iPrint version: _z9780521811415
856	4	0	_uhttps://doi.org/10.1017/CBO9781316257081
999			_c521568 _d521566