000			03257nam a22003498i 4500
001			CR9780511529818
003			UkCbUP
005			20200124160318.0
006			m|||||o||d||||||||
007			cr||||||||||||
008			090409s2001||||enk o ||1 0|eng|d
020			_a9780511529818 (ebook)
020			_z9780521770675 (hardback)
020			_z9780521018036 (paperback)
040			_aUkCbUP _beng _erda _cUkCbUP
050	0	0	_aQP406 _b.N486 2001
082	0	0	_a612.8/2 _221
245	0	0	_aNeuronal mechanisms of memory formation : _bconcepts of long-term potentiation and beyond / _cedited by Christian Hölscher.
264		1	_aCambridge : _bCambridge University Press, _c2001.
300			_a1 online resource (xiii, 493 pages) : _bdigital, PDF file(s).
336			_atext _btxt _2rdacontent
337			_acomputer _bc _2rdamedia
338			_aonline resource _bcr _2rdacarrier
500			_aTitle from publisher's bibliographic system (viewed on 05 Oct 2015).
505	0	0	_tIntroduction: Long-Term Potentiation as a Model for Memory Mechanisms: The Story So Far / _rChristian Holscher -- _gSect. 1. _tLong-Term Potentiation In Vitro and In Vivo: How Can We Fine-Tune the Current Models for Memory Formation? _g1. _tPersisting with Long-Term Potentiation as a Memory Mechanism: Clues from Variations in Long-Term Potentiation Maintenance / _rWickliffe C. Abraham. _g2. _tLong-Term Potentiation in the Amygdala: Implications for Memory / _rMichael T. Rogan, Marc G. Weisskopf and Yan-You Huang / _r[and others]. _g3. _tMultiple Roles for Synaptic Plasticity in Pavlovian Fear Conditioning / _rStephen Maren. _g4. _tPlasticity of the Hippocampal Cellular Representation of Space / _rKathryn J. Jeffery.
520			_aLong-term potentiation (LTP) is by far the most dominant model for neuronal changes that might encode memory. LTP is an elegant concept that meets many criteria set up by theoreticians long before the model's discovery, and it also fits anatomical data of learning-dependent synapse changes. Since the discovery of LTP, the question has remained about how closely LTP produced in vitro by artificial stimulation of neurons actually models putative learning-induced synaptic changes. A number of recent investigations have tried to correlate synaptic changes observed after learning with changes produced by artificial stimulation of neurons. These studies have failed to find a correlation between the two forms of synaptic plasticity. In this book, an international group of neurobiologists and psychologists discuss their latest ideas and data. The results of experiments using electrophysiological techniques in vitro are discussed and compared with the results of in vivo experiments. Learning experiments are also discussed. Theoretical models such as the Hebb theory of synaptic changes during learning are compared to different models that do not predict upregulation of synaptic transmission. A wide approach is taken, and research and models in different brain areas such as the neocortex and the basal brain are discussed.
650		0	_aMemory.
650		0	_aNeural transmission _xRegulation.
700	1		_aHölscher, Christian, _eeditor.
776	0	8	_iPrint version: _z9780521770675
856	4	0	_uhttps://doi.org/10.1017/CBO9780511529818
999			_c521632 _d521630