000			03027nam a22003498i 4500
001			CR9780511782121
003			UkCbUP
005			20200124160319.0
006			m|||||o||d||||||||
007			cr||||||||||||
008			100519s2010||||enk o ||1 0|eng|d
020			_a9780511782121 (ebook)
020			_z9780521899659 (hardback)
040			_aUkCbUP _beng _erda _cUkCbUP
050	0	0	_aQP363.2 _b.B562 2010
082	0	0	_a611/.0188 _222
245	0	4	_aThe biology of oligodendrocytes / _cedited by Patricia J. Armati and Emily K. Mathey.
264		1	_aCambridge : _bCambridge University Press, _c2010.
300			_a1 online resource (xiii, 289 pages) : _bdigital, PDF file(s).
336			_atext _btxt _2rdacontent
337			_acomputer _bc _2rdamedia
338			_aonline resource _bcr _2rdacarrier
500			_aTitle from publisher's bibliographic system (viewed on 05 Oct 2015).
505	0	0	_tCNS oligarchs: the rise of the oligodendrocyte in a neuron-centric culture / _rEmily Mathey, Ariel Arthur and Patricia Armati -- _tComparative biology of Schwann cells and oligodendrocytes / _rRudolf Martini, Janos Groh and Udo Bartsch -- _tControl of oligodendrocyte development and myelination in the vertebrate CNS / _rRobert H. Miller -- _tMolecular organization of the oligodendrocyte and myelin / _rGrahame Kidd and Bruce D. Trapp -- _tThe genetics of oligodendrocytes / _rJoseph A. Nielsen, Pierre Lau and Lynn D. Hudson -- _tImmunobiology of the oligodendrocyte / _rDavid Kremer, Orhan Aktas, Hans-Peter Hartung and Patrick Küry -- _tOligodendrocytes and disease: repair, remyelination and stem cells / _rNeil Scolding -- _tGlial progenitor cells and the dynamics of the oligodendrocyte and its myelin in the aged and injured CNS / _rJurate Lasiene and Philip J. Horner -- _tOligodendroglial pathology in multiple sclerosis / _rTanja Kuhlmann and Wolfgang Brück -- _tGlutamate receptors, transporters, and periventricular leukomalacia / _rTara M. Desilva and Paul A. Rosenberg.
520			_aTraditionally, oligodendrocytes have been assumed to play a minor supporting role in the central nervous system and their importance has generally been overlooked. For the first time, this book provides a dedicated review of all of the major aspects of oligodendrocyte biology, including development, organization, genetics, and immunobiology. Later chapters emphasize the importance of this underestimated cell to the mammalian central nervous system by exploring the role of myelin synthesis and maintenance in neural disease and repair. Particular attention is paid to multiple sclerosis (MS), arguably the prime example of an acquired demyelinating disease, with detailed examinations of the current concepts regarding demyelination, oligodendroglial damage, and remyelination in MS lesions.
650		0	_aNeuroglia.
650		0	_aMyelination.
700	1		_aArmati, Patricia J., _eeditor.
700	1		_aMathey, Emily K., _eeditor.
776	0	8	_iPrint version: _z9780521899659
856	4	0	_uhttps://doi.org/10.1017/CBO9780511782121
999			_c521773 _d521771