000			01971nam a22003378i 4500
001			CR9780511759956
003			UkCbUP
005			20200124160321.0
006			m|||||o||d||||||||
007			cr||||||||||||
008			100430s1987||||enk o ||1 0|eng|d
020			_a9780511759956 (ebook)
020			_z9780521326841 (hardback)
020			_z9780521104753 (paperback)
040			_aUkCbUP _beng _erda _cUkCbUP
050	0	0	_aRA1199.4.I5 _bV58 1987
082	0	0	_a615.9/07 _219
245	0	0	_aIn vitro methods in toxicology / _cedited by C.K. Atterwill and C.E. Steele.
264		1	_aCambridge : _bCambridge University Press, _c1987.
300			_a1 online resource (x, 458 pages) : _bdigital, PDF file(s).
336			_atext _btxt _2rdacontent
337			_acomputer _bc _2rdamedia
338			_aonline resource _bcr _2rdacarrier
500			_aTitle from publisher's bibliographic system (viewed on 05 Oct 2015).
520			_aFirst published in 1987, this book describes tissue (cell and organ) culture techniques which could be used at a critical predevelopment stage to screen for drug-inducing toxicity or to analyse the molecular mechanisms of toxicity at a later stage in parallel with investigative studies. This type of research has important ethical, financial and scientific implications. In particular, less animals and compound are required in in vitro research and more detailed information at the cellular and subcellular levels can be obtained. The volume brings together the once disparate knowledge of cultural techniques and thus provides an important reference work for industrial and academic toxicologists. It could also form a framework for discussion of potential improvements and modification of toxicity testing.
650		0	_aToxicity testing _xIn vitro.
700	1		_aAtterwill, C. K., _eeditor.
700	1		_aSteele, C. E., _eeditor.
776	0	8	_iPrint version: _z9780521326841
856	4	0	_uhttps://doi.org/10.1017/CBO9780511759956
999			_c521891 _d521889