000 03095nam a22003498i 4500
001 CR9780511541643
003 UkCbUP
005 20200124160321.0
006 m|||||o||d||||||||
007 cr||||||||||||
008 090501s2008||||enk o ||1 0|eng|d
020 _a9780511541643 (ebook)
020 _z9780521860338 (hardback)
040 _aUkCbUP
_beng
_erda
_cUkCbUP
050 0 0 _aRC628
_b.N387 2008
082 0 4 _a616.398
_222
245 0 0 _aNeurobiology of obesity /
_c[edited by] Jenni Harvey, Dominic J. Withers.
264 1 _aCambridge :
_bCambridge University Press,
_c2008.
300 _a1 online resource (xii, 324 pages) :
_bdigital, PDF file(s).
336 _atext
_btxt
_2rdacontent
337 _acomputer
_bc
_2rdamedia
338 _aonline resource
_bcr
_2rdacarrier
500 _aTitle from publisher's bibliographic system (viewed on 05 Oct 2015).
505 0 _aIntroductory chapter / Benjamin C.T. Field, Caroline J. Small and Stephen R. Bloom -- Genetics of human and rodent body weight regulation / Karine Clément -- Hypothalamic control of energy homeostasis / Neel S. Singhal and Rexford S. Ahima -- Leptin and insulin as adiposity signals / Kevin D. Niswender -- Convergence of leptin and insulin signaling networks in obesity / Calum Sutherland and Mike Ashford -- Diet-induced obesity in animal models and what they tell us about human obesity / Barry E. Levin and Alison M. Strack -- Melanocortins and the control of body weight / Virginie Tolle and Malcolm J. Low -- Role of opiate peptides in regulating energy balance / Richard J. Bodnar and Allen S. Levine -- Ghrelin : an orexigenic signal from the stomach / Tamas Horvath -- Central nervous system controls of adipose tissue apoptosis / Mary Anne Della-Fera, Mark W. Hamrick and Clifton A. Baile -- Potential therapies to limit obesity / Jason C.G. Halford.
520 _aObesity is one of the prime contributors to ill health in modern society, affecting around 20-25% of the population. It can cause or exacerbate a variety of health problems and is often associated with several other diseases including type II diabetes, coronary heart disease and certain types of cancer. Significant progress has been made in understanding the role of the nervous system and, in particular, the complex interplay between a range of orexigenic and anorectic agents within specific hypothalamic nuclei in the regulation of energy balance, appetite and adiposity. Several different neuronal pathways, neurotransmitters and hormones have been identified as major players in the regulation of feeding behavior and body weight and these are now being targeted as having therapeutic potential. Written for academic researchers and graduate students, Neurobiology of Obesity is a concise overview of recent developments in this field, written by leading international experts.
650 0 _aObesity
_xEtiology.
650 0 _aObesity
_xPathophysiology.
700 1 _aHarvey, Jenni.
700 1 _aWithers, Dominic John.
776 0 8 _iPrint version:
_z9780521860338
856 4 0 _uhttps://doi.org/10.1017/CBO9780511541643
999 _c521910
_d521908