| 000 | 02339nam a22003498i 4500 | ||
|---|---|---|---|
| 001 | CR9780511546440 | ||
| 003 | UkCbUP | ||
| 005 | 20200124160321.0 | ||
| 006 | m|||||o||d|||||||| | ||
| 007 | cr|||||||||||| | ||
| 008 | 090508s2002||||enk o ||1 0|eng|d | ||
| 020 | _a9780511546440 (ebook) | ||
| 020 | _z9780521620659 (hardback) | ||
| 020 | _z9780521018364 (paperback) | ||
| 040 |
_aUkCbUP _beng _erda _cUkCbUP |
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| 050 | 0 | 0 |
_aRM412 _b.M365 2002 |
| 082 | 0 | 0 |
_a616.9/6061 _221 |
| 100 | 1 |
_aMansour, Tag E., _eauthor. |
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| 245 | 1 | 0 |
_aChemotherapeutic targets in parasites : _bcontemporary strategies / _cTag E. Mansour ; with the assistance of Joan MacKinnon Mansour. |
| 264 | 1 |
_aCambridge : _bCambridge University Press, _c2002. |
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| 300 |
_a1 online resource (xiv, 226 pages) : _bdigital, PDF file(s). |
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| 336 |
_atext _btxt _2rdacontent |
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| 337 |
_acomputer _bc _2rdamedia |
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| 338 |
_aonline resource _bcr _2rdacarrier |
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| 500 | _aTitle from publisher's bibliographic system (viewed on 05 Oct 2015). | ||
| 520 | _aParasitic infections are the most prevalent of human diseases, and researchers continue to face the challenge of designing drugs to successfully counteract them. Chemotherapeutic Targets in Parasites analyzes the critical metabolic reactions and structural features essential for parasite survival, and advocates the latest molecular strategies with which to identify effective antiparasitic agents. An introduction to the early development of parasite chemotherapy is followed by an overview of biophysical techniques and genomic and proteomic analysis. Several chapters are devoted to specific types of chemotherapeutic agents and their targets in malaria, trypanosomes, leishmania and amitochondrial protists. Chapters on helminths include metabolic, neuromuscular, microtubular and tegumental targets. Emphasized throughout is the design of more selective and less toxic drugs than in the past. This book will be especially relevant to medical and clinical researchers and to graduate students in parasitology, pharmacology, medicine, microbiology, and biochemistry. | ||
| 650 | 0 | _aAntiparasitic agents. | |
| 650 | 0 |
_aParasitic diseases _xChemotherapy. |
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| 700 | 1 |
_aMansour, Joan MacKinnon, _eauthor. |
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| 776 | 0 | 8 |
_iPrint version: _z9780521620659 |
| 856 | 4 | 0 | _uhttps://doi.org/10.1017/CBO9780511546440 |
| 999 |
_c521932 _d521930 |
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