000 02588nam a22003738i 4500
001 CR9780511541711
003 UkCbUP
005 20200124160323.0
006 m|||||o||d||||||||
007 cr||||||||||||
008 090501s2003||||enk o ||1 0|eng|d
020 _a9780511541711 (ebook)
020 _z9780521817073 (hardback)
040 _aUkCbUP
_beng
_erda
_cUkCbUP
050 0 0 _aQP425
_b.S733 2003
082 0 0 _a612.8/21
_221
100 1 _aSteriade, Mircea,
_eauthor.
245 1 0 _aNeuronal substrates of sleep and epilepsy /
_cMircea Steriade.
246 3 _aNeuronal Substrates of Sleep & Epilepsy
264 1 _aCambridge :
_bCambridge University Press,
_c2003.
300 _a1 online resource (xii, 522 pages) :
_bdigital, PDF file(s).
336 _atext
_btxt
_2rdacontent
337 _acomputer
_bc
_2rdamedia
338 _aonline resource
_bcr
_2rdacarrier
500 _aTitle from publisher's bibliographic system (viewed on 05 Oct 2015).
505 2 _a1. Pioneering steps in studies on sleep and epilepsy 2. Neuronal types and circuits in sleep and epilepsy 3. Neuronal properties, network operations and behavioral signs during sleep states and wakefulness 4. Plastic changes in thalamocortical systems developing from low-frequency sleep oscillations 5. Neuronal mechanisms of seizures.
520 _aDifferent states of vigilance and various paroxysmal disorders that occur during slow-wave sleep can have the same neural bases. Conventional wisdom holds that sleep is a resting state of the brain, with negligible activity of cortical neurons. Here, the author brings new evidence favoring the idea that during this behavioral state memory traces acquired during waking are consolidated. The author focuses on the coalescence of different sleep rhythms in interacting corticothalamic networks and on three types of paroxysmal disorders, namely spike-wave seizures as in absence epilepsy, Lennox-Gastaut seizures, and temporal-lobe epilepsy. Many physiological correlates of waking and sleep states as well as diverse types of epileptic seizures are also discussed. The book has copious illustrations with examples from in vivo, in vitro and 'in computo' studies, the majority coming from the author's own laboratory. Neuronal Substrates of Sleep and Epilepsy is essential reading for neuroscientists and clinical researchers.
650 0 _aSleep
_xPhysiological aspects.
650 0 _aConvulsions.
650 0 _aNeurons.
650 0 _aNeural circuitry.
776 0 8 _iPrint version:
_z9780521817073
856 4 0 _uhttps://doi.org/10.1017/CBO9780511541711
999 _c522014
_d522012