000			03889nam a22003618i 4500
001			CR9780511565595
003			UkCbUP
005			20200124160331.0
006			m|||||o||d||||||||
007			cr||||||||||||
008			090518s1993||||enk o ||1 0|eng|d
020			_a9780511565595 (ebook)
020			_z9780521414265 (hardback)
020			_z9780521102797 (paperback)
040			_aUkCbUP _beng _erda _cUkCbUP
050	0	0	_aQP135 _b.G57 1993
082	0	0	_a619/.93 _220
100	1		_aGordon, Christopher J., _eauthor.
245	1	0	_aTemperature regulation in laboratory rodents / _cChristopher J. Gordon.
264		1	_aCambridge : _bCambridge University Press, _c1993.
300			_a1 online resource (xiv, 276 pages) : _bdigital, PDF file(s).
336			_atext _btxt _2rdacontent
337			_acomputer _bc _2rdamedia
338			_aonline resource _bcr _2rdacarrier
500			_aTitle from publisher's bibliographic system (viewed on 05 Oct 2015).
505	0		_aIntroduction to temperature regulation -- Brief historical perspective -- Current research status of thermoregulation -- Why study laboratory rodents? -- Overview of temperature regulation in rodents -- Do rodents provide a suitable model for human thermoregulation? -- Neurology of temperature regulation -- Temperature sensitivity of the CNS -- Neurophysiological studies -- Neuropharmacological agents -- CNS lesions and temperature regulation -- Fever -- Metabolism -- Partitioning of metabolism -- Methods for measuring metabolism -- Basal metabolism -- Metabolism during hibernation -- Maximum (peak) metabolic rate -- Metabolic thermoneutral zone -- Physical factors affecting metabolism -- Thermoregulatory effector responses -- Peripheral vasomotor tone -- Metabolic (facultative) thermogenesis -- Evaporative heat loss -- Behavioral thermoregulatory effectors -- Motor activity as a thermoregulatory effector? -- Body temperature -- Partitioning of body temperature -- Core temperature -- Brain thermal homeostasis -- Thermal tolerance -- Circadian temperature rhythm.
505	0		_a(cont) Effects of psychological stress on body temperature -- Growth, reproduction, development, and aging -- Optimal thermal conditions for growth -- Effects of thermal stress on reproductive function -- Development of thermoregulation from birth to weaning -- Aging and thermoregulation -- Temperature acclimation -- Terminology -- Acclimation to cold -- Acclimation to heat -- Gender and intraspecies differences -- Gender differences -- Intraspecies differences -- Thermoregulation during chemical toxicity, physical trauma, and other adverse environmental conditions -- Chemical toxicity -- Hypoxia and ischemia -- Trauma and shock -- Hypergravity -- Regulated hypothermia: a generalized protective mechanism?
520			_aRodents are the predominant experimental animals found in life-sciences research laboratories. The body temperature of a rodent is markedly affected by surgical, chemical or environmental manipulation. Because temperature regulation is controlled essentially by a 'holistic' regulatory system, meaning that its responses affect the activities of all other psychological and behavioural processes, it is clear that researchers working with rodents must be familiar with thermoregulatory physiology. With the help of extensive data tables and figures, this book explains the key facets of rodent thermal physiology, including neurological control and gender and intraspecies variations. There is a novel chapter on the effects of trauma, toxic chemicals and other factors. The book should therefore find use in government, academic or industrial laboratories whose researchers are working with rodents.
650		0	_aBody temperature _vRegulations.
650		0	_aPhysiology, Comparative.
776	0	8	_iPrint version: _z9780521414265
856	4	0	_uhttps://doi.org/10.1017/CBO9780511565595
999			_c522560 _d522558