000			04473nam a22003978i 4500
001			CR9781139195805
003			UkCbUP
005			20200124160335.0
006			m|||||o||d||||||||
007			cr||||||||||||
008			111109s2010||||enk o ||1 0|eng|d
020			_a9781139195805 (ebook)
020			_z9780521888745 (hardback)
040			_aUkCbUP _beng _erda _cUkCbUP
050	0	0	_aRC363 _b.I54 2010
082	0	0	_a616.8/0471 _222
245	0	0	_aInflammatory diseases of the central nervous system / _c[edited by] Trevor Kilpatrick, Richard M. Ransohoff, Steven Wesselingh.
264		1	_aCambridge : _bCambridge University Press, _c2010.
300			_a1 online resource (viii, 271 pages) : _bdigital, PDF file(s).
336			_atext _btxt _2rdacontent
337			_acomputer _bc _2rdamedia
338			_aonline resource _bcr _2rdacarrier
490	1		_aCambridge medicine
500			_aTitle from publisher's bibliographic system (viewed on 04 Jul 2016).
505	0		_aInteractions between the immune and nervous systems -- Effectors and determinants of the innate and adaptive immune responses / Edgar Meinl & Hartmut Wekerle -- Microglia: protective and pathogenic mediators / Bevyn Jarrott & Karina Apricơ -- The role of dendritic cells in neuro-inflammation / Heather Donaghy, Edwina J. Wright & Anthony L. Cunningham -- Negotiating the brain barriers: access of immune cells and pathogens into the CNS / Britta Engelghardt -- Autoimmunity -- Immune effector heterogeneity in multiple sclerosis and related CNS inflammatory demyelinating disorders Shaunu F. Roemer & Claudia F. Lucchinetti -- Multiple sclerosis : neuro-immune cross-talk in acute and progressive stages of the disease / Martin Kerschensteiner & Reinhard Hohlfeld -- CD8+ T Cell-mediated autoimmune diseases in the CNS / Lisa Walter & Matthew L. Albert -- Acute disseminated encephalomyelitis: determinants and manifestations / Eppie M. Yiu & Andrew J. Kornberg -- Primary angiitis of the CNS and its mimics / Tina Chadha, George F. Duna & Leonard H. Calabrese -- Microbiological and traumatic challenges to the CNS -- Acute viral encephalitis : role of the immune system in viral clearance from the CNS and in the generation of pathology / David N. Irani & Natalie Prow -- Chronic HIV infection of the CNS: role of the immune system in virological control and the generation of pathology / Carolyn F. Orr & Bruce J. Brew -- Brain inflammation during bacterial meningitis / Trine H. Mogensen & Lars Østergaard -- Parasitic infections of the brain: malaria and beyond / Stephen J. Rogerson & Danny A. Milner, Jr -- Role of the inflammatory process in traumatic brain damage / Cristina Morganti-Kossmann [and others] -- Therapy -- HIV-associated neurocognitive disorders: clinical features and therapeutic challenges / Nicoline Schiess & Justin C. McArthur -- Role of immunomodulation in management of infections of the CNS / Miles H. Beaman -- Neuroinflammation: an emerging therapeutic target in neurological disease / Joseph M. Antony & Christopher Power.
520			_aInteractions between the immune and nervous systems are involved in many disease processes. Modulation of inflammation can provide an important opportunity to enhance regeneration within the central nervous system. This authoritative book defines the key cellular players in mounting an inflammatory response and highlights critical factors in the target organ that influence the nature of that response and its capacity either to damage or protect the brain. Several key clinical areas are highlighted - particularly autoimmune diseases of the nervous system including multiple sclerosis, as well as microbiological and traumatic challenges; the book therefore provides both a summary of the basic science background as well as practical, clinical-friendly guidelines to management. The book will be of interest to a wide range of physicians, including neurologists, neurosurgeons, neurorehabilitationists, infectious disease physicians, and clinical neuroscientists, as well as neuroscientists and immunologists.
650		0	_aInflammation
650		0	_aAutoimmune diseases
650		0	_aCentral nervous system _xDiseases.
700	1		_aKilpatrick, Trevor, _d1959- _eeditor.
700	1		_aRansohoff, Richard M., _eeditor.
700	1		_aWesselingh, Steven, _eeditor.
776	0	8	_iPrint version: _z9780521888745
830		0	_aCambridge medicine (Series)
856	4	0	_uhttps://doi.org/10.1017/CBO9781139195805
999			_c522922 _d522920