| 000 | 02495nam a22003738i 4500 | ||
|---|---|---|---|
| 001 | CR9781108526227 | ||
| 003 | UkCbUP | ||
| 005 | 20200124160338.0 | ||
| 006 | m|||||o||d|||||||| | ||
| 007 | cr|||||||||||| | ||
| 008 | 170608s2018||||enk o ||1 0|eng|d | ||
| 020 | _a9781108526227 (ebook) | ||
| 020 | _z9781108423502 (hardback) | ||
| 040 |
_aUkCbUP _beng _erda _cUkCbUP |
||
| 050 | 0 | 0 |
_aQH601 _b.H65 2018 |
| 082 | 0 | 0 |
_a572/.577 _223 |
| 100 | 1 |
_aHoiles, William, _eauthor. |
|
| 245 | 1 | 0 |
_aDynamics of engineered artificial membranes and biosensors / _cWilliam Hoiles, Vikram Krishnamurthy, Bruce Cornell. |
| 264 | 1 |
_aCambridge : _bCambridge University Press, _c2018. |
|
| 300 |
_a1 online resource (xix, 453 pages) : _bdigital, PDF file(s). |
||
| 336 |
_atext _btxt _2rdacontent |
||
| 337 |
_acomputer _bc _2rdamedia |
||
| 338 |
_aonline resource _bcr _2rdacarrier |
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| 500 | _aTitle from publisher's bibliographic system (viewed on 29 May 2018). | ||
| 520 | _aLearn about the state of the art in building artificial membranes and synthetic biological devices, and in constructing mathematical models for their dynamics at multiple time and spatial scales with this comprehensive book. Drawing on recent advances in bioengineering and biochemistry, it describes how to engineer tethered bilayer lipid membranes, bioelectronic interfaces, high-resolution biosensors, and diagnostic devices for non-invasive cellular measurements and electroporation. Multi-physics models combining atomistic (molecular dynamics and coarse-grained molecular dynamics), mesoscopic (Poisson-Nernst-Planck), and macroscopic (reaction-rate theory) dynamics provide a complete structure-to-function description of these devices. Experiments and dynamic models explain how anti-microbial peptides penetrate membranes, how molecular machine biosensors built out of artificial membranes can detect femtomolar concentrations, and how electroporation can be controlled. Supported by atomistic simulation code online, this is essential reading for researchers, students and professionals in bioengineering, chemical engineering, biophysics, applied mathematics, and electrical engineering. | ||
| 650 | 0 | _aMembranes (Biology) | |
| 650 | 0 | _aMembranes (Technology) | |
| 650 | 0 | _aLipid membranes. | |
| 650 | 0 | _aBiosensors. | |
| 700 | 1 |
_aKrishnamurthy, V. _q(Vikram), _eauthor. |
|
| 700 | 1 |
_aCornell, Bruce, _eauthor. |
|
| 776 | 0 | 8 |
_iPrint version: _z9781108423502 |
| 856 | 4 | 0 | _uhttps://doi.org/10.1017/9781108526227 |
| 999 |
_c523268 _d523266 |
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