000 02479nam a22003858i 4500
001 CR9781108332897
003 UkCbUP
005 20200124160341.0
006 m|||||o||d||||||||
007 cr||||||||||||
008 170323s2018||||enk o ||1 0|eng|d
020 _a9781108332897 (ebook)
020 _z9781108420228 (hardback)
040 _aUkCbUP
_beng
_erda
_cUkCbUP
050 0 4 _aRS431.P75
_bP45 2018
082 0 0 _a615.7
_223
100 1 _aPfister, David,
_d1988-
_eauthor.
245 1 0 _aContinuous biopharmaceutical processes :
_bchromatography, bioconjugation, and protein stability /
_cDavid Pfister, Lucrèce Nicoud, Massimo Morbidelli.
264 1 _aCambridge :
_bCambridge University Press,
_c2018.
300 _a1 online resource (xix, 327 pages) :
_bdigital, PDF file(s).
336 _atext
_btxt
_2rdacontent
337 _acomputer
_bc
_2rdamedia
338 _aonline resource
_bcr
_2rdacarrier
490 1 _aCambridge series in chemical engineering
500 _aTitle from publisher's bibliographic system (viewed on 24 Sep 2018).
505 0 _aIntroduction to biopharmaceutical processes -- Fundamentals of protein chromatography -- Counter-current separation processes -- Counter-current chromatography for the capture step -- Counter-current chromatography for the polishing steps -- Protein conjugation -- Protein aggregation in biopharmaceutical processes.
520 _aThis innovative reference provides a coherent and critical view on the potential benefits of a transition from batch to continuous processes in the biopharmaceutical industry, with the main focus on chromatography. It also covers the key topics of protein stability and protein conjugation, addressing the chemical reaction and purification aspects together with their integration. This book offers a fine balance between theoretical modelling and illustrative case studies, between fundamental concepts and applied examples from the academic and industrial literature. Scientists interested in the design of biopharmaceutical processes will find useful practical methodologies, in particular for single-column and multi-column chromatographic processes.
650 0 _aProtein drugs.
650 0 _aPharmaceutical technology.
700 1 _aNicoud, Lucrèce,
_d1988-
_eauthor
700 1 _aMorbidelli, Massimo,
_eauthor.
776 0 8 _iPrint version:
_z9781108420228
830 0 _aCambridge series in chemical engineering.
856 4 0 _uhttps://doi.org/10.1017/9781108332897
999 _c523496
_d523494