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Fersht, Alan, 1943-

Enzyme structure and mechanism / Alan Fersht. - 2nd ed. - W.H. Freeman, c1985. - xxi, 475 p. : ill. ; 25 cm.

Includes bibliographies and index.

Contents: The three-dimensional structure of enzymes --
Chemical catalysis --
The basic equations of enzyme kinetics --
Management and magnitude of enzymatic rate constants --
The pH dependence of enzyme catalysis --
Practical kinetics --
Detection of intermediates in reactions by kinetics --
Stereochemistry of enzymatic reactions --
Active-site-directed and enzyme-activated irreversible inhibitors: "affinity labels" and "suicide inhibitors" --
Cooperative ligand binding, allosteric interactions, and regulation --
Forces between molecules, and enzyme-substrate binding energies --
Enzyme-substrate complementarity and the use of binding energy in catalysis --
Specificity and editing mechanisms --
Genetic engineering and enzymology: protein engineering --
Structures and mechanisms of selected enzymes.

ISBN: 0716716143 0716716151 (pbk.)

LCCN: 84004172

Subjects--Topical Terms:
Enzymes.
Enzymes.

Subjects--Index Terms: ბიოლოგია ბიოქიმია ენზიმები - სტრუქტურა და მექანიზმი ენზიმოლოგია

LC Class. No.: QP601 / .F42 1985

Dewey Class. No.: 574.19/25

Universal Decimal Class. No.: 577.15

National Library of Medicine Call No.: QU 135 F399e