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Enzyme structure and mechanism / Alan Fersht.

By: Material type: TextTextLanguage: English Publication details: New York : W.H. Freeman, c1985.Edition: 2nd edDescription: xxi, 475 p. : ill. ; 25 cmISBN:
  • 0716716143
  • 0716716151 (pbk.)
Subject(s): DDC classification:
  • 574.19/25 19
LOC classification:
  • QP601 .F42 1985
NLM classification:
  • QU 135 F399e
Contents:
Contents: The three-dimensional structure of enzymes -- Chemical catalysis -- The basic equations of enzyme kinetics -- Management and magnitude of enzymatic rate constants -- The pH dependence of enzyme catalysis -- Practical kinetics -- Detection of intermediates in reactions by kinetics -- Stereochemistry of enzymatic reactions -- Active-site-directed and enzyme-activated irreversible inhibitors: "affinity labels" and "suicide inhibitors" -- Cooperative ligand binding, allosteric interactions, and regulation -- Forces between molecules, and enzyme-substrate binding energies -- Enzyme-substrate complementarity and the use of binding energy in catalysis -- Specificity and editing mechanisms -- Genetic engineering and enzymology: protein engineering -- Structures and mechanisms of selected enzymes.
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Item type Current library Call number Copy number Status Date due Barcode
წიგნი წიგნი ეროვნული სამეცნიერო ბიბლიოთეკა 1 საცავი. 1 კორპ. 577.15 (Browse shelf(Opens below)) 2E40495 შესამოწმებელია 2020-5855

Includes bibliographies and index.

Contents: The three-dimensional structure of enzymes --
Chemical catalysis --
The basic equations of enzyme kinetics --
Management and magnitude of enzymatic rate constants --
The pH dependence of enzyme catalysis --
Practical kinetics --
Detection of intermediates in reactions by kinetics --
Stereochemistry of enzymatic reactions --
Active-site-directed and enzyme-activated irreversible inhibitors: "affinity labels" and "suicide inhibitors" --
Cooperative ligand binding, allosteric interactions, and regulation --
Forces between molecules, and enzyme-substrate binding energies --
Enzyme-substrate complementarity and the use of binding energy in catalysis --
Specificity and editing mechanisms --
Genetic engineering and enzymology: protein engineering --
Structures and mechanisms of selected enzymes.

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